COL5A1

COL5A1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1A89, 1A9A
Dynodwyr
Cyfenwau	COL5A1, EDSC, collagen type V alpha 1, collagen type V alpha 1 chain, EDSCL1, FMDMF
Dynodwyr allanol	OMIM: 120215 HomoloGene: 55434 GeneCards: COL5A1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • extracellular matrix structural constituent • metal ion binding • integrin binding • platelet-derived growth factor binding • proteoglycan binding • heparin binding • GO:0001948, GO:0016582 protein binding • extracellular matrix structural constituent conferring tensile strength Cydrannau o'r gell • collagen • endoplasmic reticulum lumen • collagen type V trimer • basement membrane • extracellular exosome • GO:0005578 extracellular matrix • extracellular space • extracellular region • collagen-containing extracellular matrix Prosesau biolegol • eye morphogenesis • negative regulation of endodermal cell differentiation • tendon development • wound healing, spreading of epidermal cells • integrin biosynthetic process • heart morphogenesis • regulation of cellular component organization • extracellular matrix organization • cell adhesion • blood vessel development • collagen biosynthetic process • collagen catabolic process • cell migration • skin development • collagen fibril organization • supramolecular fiber organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1289	n/a
Ensembl	ENSG00000130635	n/a
UniProt	P20908	n/a
RefSeq (mRNA)	NM_000093 NM_001278074	n/a
RefSeq (protein)	NP_000084 NP_001265003	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn COL5A1 yw COL5A1 a elwir hefyd yn Collagen type V alpha 1 chain (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q34.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn COL5A1.

• EDSC
• EDSCL1

Llyfryddiaeth

• "Human COL5A1 polymorphisms and quadriceps muscle-tendon mechanical stiffness in vivo. ". Exp Physiol. 2016. PMID 27717059.
• "Mucosal Administration of Collagen V Ameliorates the Atherosclerotic Plaque Burden by Inducing Interleukin 35-dependent Tolerance. ". J Biol Chem. 2016. PMID 26721885.
• "The BstUI and DpnII Variants of the COL5A1 Gene Are Associated With Tennis Elbow. ". Am J Sports Med. 2015. PMID 25896984.
• "Familial Ehlers-Danlos syndrome with lethal arterial events caused by a mutation in COL5A1. ". Am J Med Genet A. 2015. PMID 25845371.
• "Influence of the COL5A1 rs12722 on musculoskeletal injuries in professional soccer players.". J Sports Med Phys Fitness. 2015. PMID 25583227.