COL4A3BP

CERT1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2E3M, 2E3N, 2E3O, 2E3P, 2E3Q, 2E3R, 2E3S, 2RSG, 2Z9Y, 2Z9Z, 3H3Q, 3H3R, 3H3S, 3H3T, 4HHV
Dynodwyr
Cyfenwau	CERT1, CERT, CERTL, GPBP, STARD11, MRD34, collagen type IV alpha 3 binding protein, COL4A3BP, ceramide transporter 1
Dynodwyr allanol	OMIM: 604677 HomoloGene: 4173 GeneCards: CERT1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phosphatidylinositol-4-phosphate binding • GO:0001948, GO:0016582 protein binding • ceramide binding • lipid binding • ceramide transfer activity • kinase activity • ceramide 1-phosphate binding • ceramide 1-phosphate transfer activity Cydrannau o'r gell • cytoplasm • Golgi apparatus • endoplasmic reticulum membrane • nucleoplasm • Reticwlwm endoplasmig • perinuclear region of cytoplasm • intracellular anatomical structure • cytosol • mitocondria • bilen Prosesau biolegol • lipid transport • sphingolipid biosynthetic process • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • ER to Golgi ceramide transport • intermembrane sphingolipid transfer • GO:0000767 cell morphogenesis • in utero embryonic development • heart morphogenesis • ceramide metabolic process • muscle contraction • endoplasmic reticulum organization • GO:0072468 signal transduction • cell population proliferation • phosphorylation • response to endoplasmic reticulum stress • ceramide transport • lipid homeostasis • mitochondrion morphogenesis • intermembrane lipid transfer • ceramide 1-phosphate transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10087	n/a
Ensembl	ENSG00000113163	n/a
UniProt	Q9Y5P4	n/a
RefSeq (mRNA)	NM_001130105 NM_005713 NM_031361 NM_001379002 NM_001379003 NM_001379004 NM_001379029	n/a
RefSeq (protein)	NP_001123577 NP_005704 NP_112729 NP_001365931 NP_001365932 NP_001365933 NP_001365958	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn COL4A3BP yw COL4A3BP a elwir hefyd yn Collagen type IV alpha 3 binding protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5q13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn COL4A3BP.

• CERT
• GPBP
• CERTL
• MRD34
• STARD11

Llyfryddiaeth

• "The lipid transfer protein CERT interacts with the Chlamydia inclusion protein IncD and participates to ER-Chlamydia inclusion membrane contact sites. ". PLoS Pathog. 2011. PMID 21731489.
• "Ceramide transfer protein and cancer. ". Anticancer Agents Med Chem. 2011. PMID 21707482.
• "Interaction between the PH and START domains of ceramide transfer protein competes with phosphatidylinositol 4-phosphate binding by the PH domain. ". J Biol Chem. 2017. PMID 28652409.
• "Structural basis for the Golgi association by the pleckstrin homology domain of the ceramide trafficking protein (CERT). ". J Biol Chem. 2012. PMID 22869376.
• "Inactivation of ceramide transfer protein during pro-apoptotic stress by Golgi disassembly and caspase cleavage.". Biochem J. 2012. PMID 22129459.