CMPK1

CMPK1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1TEV
Dynodwyr
Cyfenwau	CMPK1, CK, CMK, CMPK, UMK, UMP-CMPK, UMPK, cytidine/uridine monophosphate kinase 1
Dynodwyr allanol	OMIM: 191710 HomoloGene: 32308 GeneCards: CMPK1
EC number	2.7.4.6
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • uridylate kinase activity • kinase activity • nucleobase-containing compound kinase activity • uridine kinase activity • nucleoside diphosphate kinase activity • ATP binding • cytidylate kinase activity • nucleoside monophosphate kinase activity Cydrannau o'r gell • cytoplasm • cytosol • extracellular exosome • cnewyllyn cell • nucleolus Prosesau biolegol • nucleobase-containing small molecule interconversion • phosphorylation • nucleoside diphosphate phosphorylation • pyrimidine ribonucleotide biosynthetic process • pyrimidine nucleotide biosynthetic process • 'de novo' pyrimidine nucleobase biosynthetic process • nucleoside triphosphate biosynthetic process • nucleobase-containing compound metabolic process • nucleoside monophosphate phosphorylation • UMP biosynthetic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51727	n/a
Ensembl	ENSG00000162368	n/a
UniProt	P30085	n/a
RefSeq (mRNA)	NM_001136140 NM_016308 NM_001366135	n/a
RefSeq (protein)	NP_001129612 NP_057392 NP_001353064	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CMPK1 yw CMPK1 a elwir hefyd yn Cytidine/uridine monophosphate kinase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CMPK1.

• CK
• CMK
• UMK
• CMPK
• UMPK
• UMP-CMPK

Llyfryddiaeth

• "Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives -- a screening based on affinity for the UMP-CMP binding site. ". FEBS J. 2007. PMID 17608725.
• "Phosphorylation of Cytidine, Deoxycytidine, and Their Analog Monophosphates by Human UMP/CMP Kinase Is Differentially Regulated by ATP and Magnesium. ". Mol Pharmacol. 2005. PMID 15550676.
• "The contribution of CMP kinase to the efficiency of DNA repair. ". Cell Cycle. 2015. PMID 25659034.
• "Effect of genetic polymorphisms on therapeutic response and clinical outcomes in pancreatic cancer patients treated with gemcitabine. ". Pharmacogenomics. 2012. PMID 22838950.
• "UMP/CMPK is not the critical enzyme in the metabolism of pyrimidine ribonucleotide and activation of deoxycytidine analogs in human RKO cells.". PLoS One. 2011. PMID 21559290.