CMA1

CMA1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3S0N, 1NN6, 4AFS, 1PJP, 1T31, 2HVX, 3N7O, 4AG1, 4K69, 4KP0, 1KLT, 4AFZ, 4AG2, 4K2Y, 4K60, 4AFU, 4K5Z, 4AFQ
Dynodwyr
Cyfenwau	CMA1, CYH, MCT1, chymase, chymase 1
Dynodwyr allanol	OMIM: 118938 HomoloGene: 55606 GeneCards: CMA1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peptide binding • GO:0070122 peptidase activity • serine-type endopeptidase activity • hydrolase activity • serine-type peptidase activity • endopeptidase activity Cydrannau o'r gell • GO:0005578 extracellular matrix • secretory granule • extracellular region • extracellular space • cytoplasm • collagen-containing extracellular matrix Prosesau biolegol • peptide metabolic process • angiotensin maturation • proteolysis • positive regulation of angiogenesis • regulation of inflammatory response • midbrain development • cellular response to glucose stimulus • extracellular matrix disassembly • basement membrane disassembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1215	n/a
Ensembl	ENSG00000092009	n/a
UniProt	P23946	n/a
RefSeq (mRNA)	NM_001308083 NM_001836	n/a
RefSeq (protein)	NP_001295012 NP_001827	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CMA1 yw CMA1 a elwir hefyd yn Chymase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 14, band 14q12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CMA1.

• CYH
• MCT1
• chymase

Llyfryddiaeth

• "[Association of CMA1 gene tag single nucleotide polymorphisms with essential hypertension in Yi population from Yunnan]. ". Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2014. PMID 25119908.
• "[Renin-angiotensin-aldosterone system in hypertrophic cardiomyopathy]. ". Kardiologiia. 2014. PMID 25102745.
• "Altered immunohistochemical expression of mast cell tryptase and chymase in the pathogenesis of oral submucous fibrosis and malignant transformation of the overlying epithelium. ". PLoS One. 2014. PMID 24874976.
• "Association of the common genetic polymorphisms and haplotypes of the chymase gene with left ventricular mass in male patients with symptomatic aortic stenosis. ". PLoS One. 2014. PMID 24823657.
• "Chymase activities and survival in endotoxin-induced human chymase transgenic mice.". Int J Med Sci. 2014. PMID 24516344.