CKS2

CKS2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1CKS, 4Y72, 5HQ0, 4YC3
Dynodwyr
Cyfenwau	CKS2, CKSHS2, CDC28 protein kinase regulatory subunit 2
Dynodwyr allanol	OMIM: 116901 HomoloGene: 86883 GeneCards: CKS2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • cyclin-dependent protein serine/threonine kinase regulator activity • chromatin binding • GO:0031493 histone binding • protein kinase binding • GO:0016534 cyclin-dependent protein serine/threonine kinase activator activity • ubiquitin binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • SCF ubiquitin ligase complex • cyclin-dependent protein kinase holoenzyme complex Prosesau biolegol • cell cycle • meiosis I • Cellraniad • regulation of mitotic cell cycle • positive regulation of cyclin-dependent protein serine/threonine kinase activity • cell population proliferation • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • GO:0007090 mitotic cell cycle phase transition • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • regulation of cyclin-dependent protein serine/threonine kinase activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1164	n/a
Ensembl	ENSG00000123975	n/a
UniProt	P33552	n/a
RefSeq (mRNA)	NM_001827	n/a
RefSeq (protein)	NP_001818	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CKS2 yw CKS2 a elwir hefyd yn CDC28 protein kinase regulatory subunit 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q22.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CKS2.

• CKSHS2

Llyfryddiaeth

• "Expression of cyclin kinase subunit 2 in human breast cancer and its prognostic significance. ". Int J Clin Exp Pathol. 2014. PMID 25674223.
• "Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints. ". Oncogene. 2015. PMID 24858038.
• "Clinical and biological impact of cyclin-dependent kinase subunit 2 in esophageal squamous cell carcinoma. ". Oncol Rep. 2014. PMID 24604089.
• "Oncogenic potential of cyclin kinase subunit-2 in cholangiocarcinoma. ". Liver Int. 2013. PMID 23121546.
• "Cyclin-dependent kinase-associated protein Cks2 is associated with bladder cancer progression.". J Int Med Res. 2011. PMID 21672358.