CHMP6

CHMP6
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2K3W, 3HTU
Dynodwyr
Cyfenwau	CHMP6, VPS20, charged multivesicular body protein 6
Dynodwyr allanol	OMIM: 610901 HomoloGene: 11607 GeneCards: CHMP6
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein N-terminus binding • GO:0001948, GO:0016582 protein binding • GO:0032403 protein-containing complex binding Cydrannau o'r gell • ESCRT III complex • cytosol • endosome • bilen • late endosome membrane • endosome membrane • extracellular exosome • endomembrane system Prosesau biolegol • GO:0019067 viral life cycle • nucleus organization • regulation of exosomal secretion • multivesicular body assembly • ESCRT III complex assembly • endosomal transport • protein transport • septum digestion after cytokinesis • mitotic metaphase plate congression • vacuolar transport • macroautophagy • negative regulation of epidermal growth factor-activated receptor activity • GO:0015915 transport • GO:1903362 regulation of protein catabolic process • midbody abscission Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	79643	n/a
Ensembl	ENSG00000176108	n/a
UniProt	Q96FZ7	n/a
RefSeq (mRNA)	NM_024591	n/a
RefSeq (protein)	NP_078867	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CHMP6 yw CHMP6 a elwir hefyd yn Charged multivesicular body protein 6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q25.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CHMP6.

• VPS20

Llyfryddiaeth

• "Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis. ". Dev Cell. 2009. PMID 19686684.
• "Avian sarcoma virus and human immunodeficiency virus, type 1 use different subsets of ESCRT proteins to facilitate the budding process. ". J Biol Chem. 2008. PMID 18723511.
• "The VPS-20 subunit of the endosomal sorting complex ESCRT-III exhibits an open conformation in the absence of upstream activation. ". Biochem J. 2015. PMID 25588614.
• "Overexpression of CHMP6 induces cellular oncosis and apoptosis in HeLa cells. ". Biosci Biotechnol Biochem. 2009. PMID 19270365.
• "Inhibition of ESCRT-II-CHMP6 interactions impedes cytokinetic abscission and leads to cell death.". Mol Biol Cell. 2014. PMID 25232011.