CHMP3

CHMP3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2XZE, 3FRT, 3FRV, 2GD5
Dynodwyr
Cyfenwau	CHMP3, NEDF, VPS24, CGI-149, charged multivesicular body protein 3
Dynodwyr allanol	OMIM: 610052 HomoloGene: 6368 GeneCards: CHMP3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • phosphatidylcholine binding • protein homodimerization activity • ubiquitin-specific protease binding • identical protein binding Cydrannau o'r gell • cytoplasm • bilen • Cellbilen • endosome • late endosome membrane • extracellular exosome • ESCRT III complex • cytosol • intracellular anatomical structure • late endosome • GO:0016023 cytoplasmic vesicle • multivesicular body Prosesau biolegol • GO:0000046 autophagosome maturation • GO:0019067 viral life cycle • protein polymerization • multivesicular body assembly • cell cycle • Cellraniad • regulation of mitotic spindle assembly • endosomal transport • regulation of centrosome duplication • GO:0097285 apoptotic process • protein heterooligomerization • vacuolar transport • septum digestion after cytokinesis • protein transport • nucleus organization • mitotic metaphase plate congression • multivesicular body sorting pathway • regulation of exosomal secretion • macroautophagy • multivesicular body-lysosome fusion • regulation of early endosome to late endosome transport • GO:0015915 transport • viral budding via host ESCRT complex • endosome transport via multivesicular body sorting pathway • late endosome to vacuole transport • midbody abscission Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51652	n/a
Ensembl	ENSG00000115561	n/a
UniProt	Q9Y3E7	n/a
RefSeq (mRNA)	NM_001005753 NM_001193517 NM_016079	n/a
RefSeq (protein)	NP_001005753 NP_001180446 NP_057163	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CHMP3 yw CHMP3 a elwir hefyd yn Charged multivesicular body protein 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2p11.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CHMP3.

• NEDF
• VPS24
• CGI-149

Llyfryddiaeth

• "Activation of human VPS4A by ESCRT-III proteins reveals ability of substrates to relieve enzyme autoinhibition. ". J Biol Chem. 2010. PMID 20805225.
• "Structural basis for budding by the ESCRT-III factor CHMP3. ". Dev Cell. 2006. PMID 16740483.
• "Intracellular trafficking and maturation of herpes simplex virus type 1 gB and virus egress require functional biogenesis of multivesicular bodies. ". J Virol. 2007. PMID 17686835.
• "Characterization of a novel alternatively spliced human transcript encoding an N-terminally truncated Vps24 protein that suppresses the effects of Bax in an ESCRT independent manner in yeast. ". Gene. 2007. PMID 17331679.
• "mVps24p functions in EGF receptor sorting/trafficking from the early endosome.". Exp Cell Res. 2005. PMID 15707591.