CHD1

CHD1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2B2T, 2B2U, 2B2V, 2B2W, 2B2Y, 4B4C, 4NW2, 4O42, 5AFW, 2N39
Dynodwyr
Cyfenwau	CHD1, chromodomain helicase DNA binding protein 1, PILBOS, CHD-1
Dynodwyr allanol	OMIM: 602118 HomoloGene: 68174 GeneCards: CHD1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • GO:0004003 DNA helicase activity • nucleotide binding • GO:0001948, GO:0016582 protein binding • hydrolase activity • ATP binding • GO:0008026 helicase activity • methylated histone binding Cydrannau o'r gell • cytoplasm • cnewyllyn cell • fibrillar center • nucleoplasm Prosesau biolegol • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • chromatin remodeling • GO:0009373 regulation of transcription, DNA-templated • positive regulation by host of viral transcription • transcription, DNA-templated • DNA duplex unwinding • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1105	n/a
Ensembl	ENSG00000153922	n/a
UniProt	O14646	n/a
RefSeq (mRNA)	NM_001270 NM_001364113 NM_001376194	n/a
RefSeq (protein)	NP_001261 NP_001351042 NP_001363123	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CHD1 yw CHD1 a elwir hefyd yn Chromodomain-helicase-DNA-binding protein 1 a Chromodomain helicase DNA binding protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5q15-q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CHD1.

• PILBOS

Llyfryddiaeth

• "Missense variants in the chromatin remodeler CHD1are associated with neurodevelopmental disability. ". J Med Genet. 2017. PMID 28866611.
• "CHD1L Expression Increases Tumor Progression and Acts as a Predictive Biomarker for Poor Prognosis in Pancreatic Cancer. ". Dig Dis Sci. 2017. PMID 28646284.
• "CHD1 regulates cell fate determination by activation of differentiation-induced genes. ". Nucleic Acids Res. 2017. PMID 28475736.
• "Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness. ". EMBO Rep. 2016. PMID 27596623.
• "Influenza Virus and Chromatin: Role of the CHD1 Chromatin Remodeler in the Virus Life Cycle.". J Virol. 2016. PMID 26792750.