CGA

CGA
Strwythurau PDB Orthologau:PDBe RCSB Rhestr o ddynodwyr PDB 1DZ7, 1E9J, 1FL7, 1HCN, 1HD4, 1HRP, 1QFW, 1XWD, 4AY9, 4MQW
Dynodwyr
Cyfenwau	CGA, CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA, Chorionic gonadotropin alpha, glycoprotein hormones, alpha polypeptide, Alpha subunit of glycoprotein hormones, GPA1
Dynodwyr allanol	OMIM: 118850 MGI: 88390 HomoloGene: 587 GeneCards: CGA
Lleoliad y genyn (llygoedn) Cr. Cromosom 4 (llygoden) Band 4 A5|4 16.86 cM Start 34,893,779 bp End 34,907,370 bp
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein binding • hormone activity • follicle-stimulating hormone activity Cydrannau o'r gell • Golgi lumen • extracellular region • extracellular space • follicle-stimulating hormone complex Prosesau biolegol • cell-cell signaling • peptide hormone processing • positive regulation of cell proliferation • positive regulation of transcription from RNA polymerase II promoter • signal transduction • positive regulation of cell migration • regulation of transcription from RNA polymerase II promoter • regulation of receptor activity • G-protein coupled receptor signaling pathway • positive regulation of steroid biosynthetic process • thyroid hormone generation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1081	12640
Ensembl	ENSG00000135346	ENSMUSG00000028298
UniProt	P01215	P01216
RefSeq (mRNA)	NM_001252383 NM_000735	NM_009889
RefSeq (protein)	NP_000726 NP_001239312	NP_034019
Lleoliad (UCSC)	n/a	Chr : 34.89 – 34.91 Mb
PubMed search
Wicidata
Gweld/Golygu Bod dynol Gweld/Golygu Llygoden

Protein sy'n cael ei godio yn y corff dynol gan y genyn CGA yw CGA a elwir hefyd yn Glycoprotein hormones alpha chain a Glycoprotein hormones, alpha polypeptide (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6q14.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CGA.

• HCG
• LHA
• FSHA
• GPHa
• TSHA
• GPHA1
• CG-ALPHA

Llyfryddiaeth

• "Modulating the endometrial epithelial proteome and secretome in preparation for pregnancy: The role of ovarian steroid and pregnancy hormones. ". J Proteomics. 2016. PMID 27262222.
• "Human Chorionic Gonadotropin Protects Vascular Endothelial Cells from Oxidative Stress by Apoptosis Inhibition, Cell Survival Signalling Activation and Mitochondrial Function Protection. ". Cell Physiol Biochem. 2015. PMID 26279419.
• "Limitations in the process of transcription and translation inhibit recombinant human chorionic gonadotropin expression in CHO cells. ". J Biotechnol. 2015. PMID 25529346.
• "TSH elevations as the first laboratory evidence for pseudohypoparathyroidism type Ib (PHP-Ib). ". J Bone Miner Res. 2015. PMID 25403028.
• "Low serum thyrotropin level and duration of suppression as a predictor of major osteoporotic fractures-the OPENTHYRO register cohort.". J Bone Miner Res. 2014. PMID 24723381.