CFL1

CFL1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4BEX, 1Q8G, 1Q8X, 3J0S, 5HVK, 5L6W
Dynodwyr
Cyfenwau	CFL1, CFL, HEL-S-15, cofilin, cofilin 1
Dynodwyr allanol	OMIM: 601442 HomoloGene: 99735 GeneCards: CFL1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • actin binding • actin filament binding • signaling receptor binding Cydrannau o'r gell • cytoplasm • fesigl • cell projection • bilen • focal adhesion • nuclear matrix • Cellbilen • intracellular anatomical structure • ruffle membrane • actin cytoskeleton • Cytosgerbwd • lamellipodium membrane • extracellular exosome • cnewyllyn cell • GO:0005578 extracellular matrix • extracellular space • cell-cell junction • cortical actin cytoskeleton • cytosol • lamellipodium Prosesau biolegol • response to virus • negative regulation of apoptotic process • positive regulation by host of viral process • cytoskeleton organization • Rho protein signal transduction • regulation of cell morphogenesis • regulation of dendritic spine morphogenesis • actin cytoskeleton organization • actin filament depolymerization • mitotic cytokinesis • neural crest cell migration • neural fold formation • protein phosphorylation • actin filament organization • establishment of cell polarity • actin filament fragmentation • positive regulation of actin filament depolymerization • response to amino acid • interleukin-12-mediated signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1072	n/a
Ensembl	ENSG00000172757	n/a
UniProt	P23528	n/a
RefSeq (mRNA)	NM_005507	n/a
RefSeq (protein)	NP_005498	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CFL1 yw CFL1 a elwir hefyd yn Cofilin 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q13.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CFL1.

• CFL
• cofilin
• HEL-S-15

Llyfryddiaeth

• "Cofilin is a cAMP effector in mediating actin cytoskeleton reorganization and steroidogenesis in mouse and human adrenocortical tumor cells. ". Cancer Lett. 2017. PMID 28826686.
• "Immune-complex level of cofilin-1 in sera is associated with cancer progression and poor prognosis in pancreatic cancer. ". Cancer Sci. 2017. PMID 28161904.
• "Study on the significance of Cofilin 1 overexpression in human bladder cancer. ". Tumori. 2017. PMID 27768223.
• "Association of epithelial-mesenchymal transition and nuclear cofilin with advanced urothelial cancer. ". Hum Pathol. 2016. PMID 27402302.
• "The role of cofilin-l in vulvar squamous cell carcinoma: A marker of carcinogenesis, progression and targeted therapy.". Oncol Rep. 2016. PMID 26936386.