CELF2

CELF2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2MY7, 2MY8, 4LJM, 4LMZ, 4TLQ
Dynodwyr
Cyfenwau	CELF2, BRUNOL3, CUGBP2, ETR-3, ETR3, NAPOR, CELF-2, CUG-BP2, CUGBP, Elav-like family member 2, CUGBP Elav-like family member 2, DEE97
Dynodwyr allanol	OMIM: 602538 HomoloGene: 4783 GeneCards: CELF2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleic acid binding • RNA binding • pre-mRNA binding • mRNA binding Cydrannau o'r gell • cytoplasm • cnewyllyn cell • ribonucleoprotein complex Prosesau biolegol • mRNA processing • GO:0033168, GO:0036404, GO:1902360 RNA processing • regulation of heart contraction • mRNA splice site selection • regulation of alternative mRNA splicing, via spliceosome Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10659	n/a
Ensembl	ENSG00000048740	n/a
UniProt	O95319	n/a
RefSeq (mRNA)	NM_001025076 NM_001025077 NM_001083591 NM_006561 NM_001326317 NM_001326318 NM_001326319 NM_001326320 NM_001326321 NM_001326323 NM_001326324 NM_001326325 NM_001326326 NM_001326327 NM_001326328 NM_001326329 NM_001326330 NM_001326331 NM_001326332 NM_001326333 NM_001326334 NM_001326335 NM_001326336 NM_001326337 NM_001326338 NM_001326339 NM_001326340 NM_001326341 NM_001326342 NM_001326343 NM_001326344 NM_001326345 NM_001326346 NM_001326347 NM_001326348 NM_001326349 NM_001394502 NM_001394513 NM_001394517 NM_001394518 NM_001394519	n/a
RefSeq (protein)	NP_001020247 NP_001020248 NP_001077060 NP_001313246 NP_001313247 NP_001313248 NP_001313249 NP_001313250 NP_001313252 NP_001313253 NP_001313254 NP_001313255 NP_001313256 NP_001313257 NP_001313258 NP_001313259 NP_001313260 NP_001313261 NP_001313262 NP_001313263 NP_001313264 NP_001313265 NP_001313266 NP_001313267 NP_001313268 NP_001313269 NP_001313270 NP_001313271 NP_001313272 NP_001313273 NP_001313274 NP_001313275 NP_001313276 NP_001313277 NP_001313278 NP_006552	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CELF2 yw CELF2 a elwir hefyd yn CUGBP Elav-like family member 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 10, band 10p14.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CELF2.

• ETR3
• ETR-3
• NAPOR
• CELF-2
• CUGBP2
• BRUNOL3
• CUG-BP2

Llyfryddiaeth

• "Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling. ". Proc Natl Acad Sci U S A. 2015. PMID 25870297.
• "CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe. ". Am J Physiol Gastrointest Liver Physiol. 2008. PMID 18325984.
• "Position-dependent activity of CELF2 in the regulation of splicing and implications for signal-responsive regulation in T cells. ". RNA Biol. 2016. PMID 27096301.
• "Upregulation of cugbp2 increases response of pancreatic cancer cells to chemotherapy. ". Langenbecks Arch Surg. 2016. PMID 26691217.
• "Association of CELF2 polymorphism and the prognosis of nasopharyngeal carcinoma in southern Chinese population.". Oncotarget. 2015. PMID 26314850.