CDON

CDON
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3D1M, 3N1F, 3N1Q
Dynodwyr
Cyfenwau	CDON, CDO, CDON1, HPE11, ORCAM, cell adhesion associated, oncogene regulated, Ihog
Dynodwyr allanol	OMIM: 608707 HomoloGene: 22996 GeneCards: CDON
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • integral component of membrane • bilen • GO:0005578 extracellular matrix • Cellbilen • integral component of plasma membrane • collagen-containing extracellular matrix Prosesau biolegol • regulation of neuron differentiation • positive regulation of small GTPase mediated signal transduction • positive regulation of protein phosphorylation • regulation of protein heterodimerization activity • positive regulation of skeletal muscle tissue development • positive regulation of muscle cell differentiation • embryonic body morphogenesis • cell fate specification • skeletal muscle satellite cell differentiation • positive regulation of neural precursor cell proliferation • lens development in camera-type eye • positive regulation of myoblast differentiation • embryonic morphogenesis • positive regulation of neuron differentiation • cerebral cortex development • embryonic retina morphogenesis in camera-type eye • smoothened signaling pathway • striated muscle cell differentiation • myoblast fusion • anterior/posterior pattern specification • positive regulation of MAPK cascade • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • cell adhesion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	50937	n/a
Ensembl	ENSG00000064309	n/a
UniProt	Q4KMG0	n/a
RefSeq (mRNA)	NM_001243597 NM_016952 NM_001378964	n/a
RefSeq (protein)	NP_001230526 NP_058648 NP_001365893	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CDON yw CDON a elwir hefyd yn Cell adhesion molecule-related/down-regulated by oncogenes a Cell adhesion associated, oncogene regulated (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q24.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CDON.

• CDO
• CDON1
• HPE11
• ORCAM

Llyfryddiaeth

• "Identification of transmembrane protein in prostate cancer by the Escherichia coli ampicillin secretion trap: expression of CDON is involved in tumor cell growth and invasion. ". Pathobiology. 2011. PMID 21849809.
• "Regulation by miR181 family of the dependence receptor CDON tumor suppressive activity in neuroblastoma. ". J Natl Cancer Inst. 2014. PMID 25313246.
• "A Nonsense Mutation in the Hedgehog Receptor CDON Associated With Pituitary Stalk Interruption Syndrome. ". J Clin Endocrinol Metab. 2016. PMID 26529631.
• "CDO, an Hh-coreceptor, mediates lung cancer cell proliferation and tumorigenicity through Hedgehog signaling. ". PLoS One. 2014. PMID 25369201.
• "Cdon and Boc: Two transmembrane proteins implicated in cell-cell communication.". Int J Biochem Cell Biol. 2012. PMID 22326621.