CDKN3

CDKN3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1FPZ, 1FQ1
Dynodwyr
Cyfenwau	CDKN3, CDI1, CIP2, KAP, KAP1, cyclin-dependent kinase inhibitor 3, cyclin dependent kinase inhibitor 3, CDLN3
Dynodwyr allanol	OMIM: 123832 HomoloGene: 3805 GeneCards: CDKN3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0098519, GO:0098518 phosphatase activity • protein serine/threonine phosphatase activity • phosphoprotein phosphatase activity • hydrolase activity • GO:0001948, GO:0016582 protein binding • protein tyrosine/serine/threonine phosphatase activity • protein tyrosine phosphatase activity Cydrannau o'r gell • cnewyllyn cell • perinuclear region of cytoplasm • cytoplasm • cytosol Prosesau biolegol • cell cycle • regulation of cyclin-dependent protein serine/threonine kinase activity • negative regulation of cell population proliferation • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • peptidyl-tyrosine dephosphorylation • GO:0016576 protein dephosphorylation • G1/S transition of mitotic cell cycle Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1033	n/a
Ensembl	ENSG00000100526	n/a
UniProt	Q16667	n/a
RefSeq (mRNA)	NM_001130851 NM_005192 NM_001330173	n/a
RefSeq (protein)	NP_001124323 NP_001317102 NP_005183	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CDKN3 yw CDKN3 a elwir hefyd yn Cyclin dependent kinase inhibitor 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 14, band 14q22.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CDKN3.

• KAP
• CDI1
• CIP2
• KAP1

Llyfryddiaeth

• "Expression and alternative splicing of the cyclin-dependent kinase inhibitor-3 gene in human cancer. ". Int J Biochem Cell Biol. 2017. PMID 28504190.
• "Knockdown of Cyclin-Dependent Kinase Inhibitor 3 Inhibits Proliferation and Invasion in Human Gastric Cancer Cells. ". Oncol Res. 2017. PMID 27983933.
• "Silencing cyclin-dependent kinase inhibitor 3 inhibits the migration of breast cancer cell lines. ". Mol Med Rep. 2016. PMID 27314680.
• "CDKN3 expression is negatively associated with pathological tumor stage and CDKN3 inhibition promotes cell survival in hepatocellular carcinoma. ". Mol Med Rep. 2016. PMID 27314282.
• "Overexpression of major CDKN3 transcripts is associated with poor survival in lung adenocarcinoma.". Br J Cancer. 2015. PMID 26554648.