CDC5L Dynodwyr Cyfenwau CDC5L Dynodwyr allanol OMIM: 602868 HomoloGene: 13291 GeneCards: CDC5L Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • protein phosphatase 1 binding • leucine zipper domain binding • WD40-repeat domain binding • GO:0001948, GO:0016582 protein binding • transcription corepressor binding • protein kinase binding • sequence-specific DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • RNA binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific Cydrannau o'r gell • cytoplasm • nuclear speck • catalytic step 2 spliceosome • bilen • Prp19 complex • nucleoplasm • protein-DNA complex • perinuclear region of cytoplasm • DNA replication factor A complex • spliceosomal complex • cnewyllyn cell • U2-type catalytic step 2 spliceosome Prosesau biolegol • mRNA splicing, via spliceosome • cellular response to nerve growth factor stimulus • GO:0009373 regulation of transcription, DNA-templated • mRNA processing • cellular response to fibroblast growth factor stimulus • transcription, DNA-templated • cellular response to interleukin-2 • cellular response to prolactin • cellular response to DNA damage stimulus • cellular response to wortmannin • GO:0007067 Mitosis • cell cycle • GO:0100026 DNA repair • cell differentiation • RNA splicing • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • transcription by RNA polymerase II • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau Species Bod dynol Llygoden Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Lleoliad (UCSC) n/a n/a PubMed search[1] n/a Wicidata
Protein sy'n cael ei godio yn y corff dynol gan y genyn CDC5L yw CDC5L a elwir hefyd yn Cell division cycle 5 like (Saesneg). Segment o DNA yw'r genyn , sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6p21.1.[2]
Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CDC5L.
CDC5
CEF1
PCDC5RP
CDC5-LIKE
dJ319D22.1
"Expression and Clinical Role of Cdc5L as a Novel Cell Cycle Protein in Hepatocellular Carcinoma. ". Dig Dis Sci . 2016. PMID 26553251 . "Expression of CDC5L is associated with tumor progression in gliomas. ". Tumour Biol . 2016. PMID 26490980 . "Depletion of pre-mRNA splicing factor Cdc5L inhibits mitotic progression and triggers mitotic catastrophe. ". Cell Death Dis . 2014. PMID 24675469 . "Cell cycle-dependent phosphorylation of human CDC5 regulates RNA processing. ". Cell Cycle . 2008. PMID 18583928 . "Distinct domains of human CDC5 direct its nuclear import and association with the spliceosome. ". Cell Biochem Biophys . 2003. PMID 14515018 . 
