CDC34

CDC34
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2OB4, 3RZ3, 4MDK
Dynodwyr
Cyfenwau	CDC34, E2-UBC3, UBCH3, UBE2R1, cell division cycle 34, cell division cycle 34, ubiqiutin conjugating enzyme
Dynodwyr allanol	OMIM: 116948 HomoloGene: 55815 GeneCards: CDC34
EC number	2.3.2.24
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • GO:0050372 ubiquitin-protein transferase activity • GO:0001948, GO:0016582 protein binding • ATP binding • ubiquitin conjugating enzyme activity • ubiquitin protein ligase binding Cydrannau o'r gell • cnewyllyn cell • nucleoplasm • cytoplasm • cytosol • nuclear speck Prosesau biolegol • negative regulation of cAMP-mediated signaling • cellular response to interferon-beta • protein polyubiquitination • positive regulation of inclusion body assembly • protein K48-linked ubiquitination • positive regulation of neuron apoptotic process • DNA replication initiation • cell cycle • response to growth factor • proteasome-mediated ubiquitin-dependent protein catabolic process • protein ubiquitination • G1/S transition of mitotic cell cycle • ubiquitin-dependent protein catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	997	n/a
Ensembl	ENSG00000099804	n/a
UniProt	P49427	n/a
RefSeq (mRNA)	NM_004359	n/a
RefSeq (protein)	NP_004350	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CDC34 yw CDC34 a elwir hefyd yn Ubiquitin-conjugating enzyme E2 R1 a Cell division cycle 34 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CDC34.

• UBC3
• UBCH3
• UBE2R1
• E2-CDC34

Llyfryddiaeth

• "Association of the disordered C-terminus of CDC34 with a catalytically bound ubiquitin. ". J Mol Biol. 2011. PMID 21296085.
• "Human Cdc34 employs distinct sites to coordinate attachment of ubiquitin to a substrate and assembly of polyubiquitin chains. ". Mol Cell Biol. 2007. PMID 17698585.
• "Proximity-induced activation of human Cdc34 through heterologous dimerization. ". Proc Natl Acad Sci U S A. 2005. PMID 16210246.
• "Association of human ubiquitin-conjugating enzyme CDC34 with the mitotic spindle in anaphase. ". J Cell Sci. 2000. PMID 10769200.
• "Cell cycle regulation by the ubiquitin pathway.". FASEB J. 1997. PMID 9367342.