CDC25C

CDC25C
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2OJX, 3BZI, 3OP3
Dynodwyr
Cyfenwau	CDC25C, CDC25, PPP1R60, cell division cycle 25C
Dynodwyr allanol	OMIM: 157680 HomoloGene: 1356 GeneCards: CDC25C
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • WW domain binding • protein tyrosine phosphatase activity • hydrolase activity • protein kinase binding • phosphoprotein phosphatase activity Cydrannau o'r gell • cytoplasm • cytosol • intracellular anatomical structure • nucleoplasm • perinuclear region of cytoplasm • cnewyllyn cell • nuclear speck Prosesau biolegol • regulation of cyclin-dependent protein serine/threonine kinase activity • GO:0016576 protein dephosphorylation • regulation of cell cycle • Cellraniad • DNA replication • G2/M transition of mitotic cell cycle • spermatogenesis • cell cycle • cell population proliferation • GO:0022415 viral process • regulation of mitotic nuclear division • peptidyl-tyrosine dephosphorylation • DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest • positive regulation of cell cycle G2/M phase transition • positive regulation of G2/M transition of mitotic cell cycle • positive regulation of mitotic cell cycle • positive regulation of G2/MI transition of meiotic cell cycle Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	995	n/a
Ensembl	ENSG00000158402	n/a
UniProt	P30307	n/a
RefSeq (mRNA)	NM_001287582 NM_001287583 NM_001790 NM_022809 NM_001318098 NM_001364026 NM_001364027 NM_001364028	n/a
RefSeq (protein)	NP_001274511 NP_001274512 NP_001305027 NP_001781 NP_073720 NP_001350955 NP_001350956 NP_001350957	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CDC25C yw CDC25C a elwir hefyd yn Cell division cycle 25C (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5q31.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CDC25C.

• CDC25
• PPP1R60

Llyfryddiaeth

• "Downregulation of cell division cycle 25 homolog C reduces the radiosensitivity and proliferation activity of esophageal squamous cell carcinoma. ". Gene. 2016. PMID 27188256.
• "Phosphatases and kinases regulating CDC25 activity in the cell cycle: clinical implications of CDC25 overexpression and potential treatment strategies. ". Mol Cell Biochem. 2016. PMID 27038604.
• "Cell cycle-dependent Cdc25C phosphatase determines cell survival by regulating apoptosis signal-regulating kinase 1. ". Cell Death Differ. 2015. PMID 25633196.
• "Recurrent CDC25C mutations drive malignant transformation in FPD/AML. ". Nat Commun. 2014. PMID 25159113.
• "Androgens upregulate Cdc25C protein by inhibiting its proteasomal and lysosomal degradation pathways.". PLoS One. 2013. PMID 23637932.