CDC25A

CDC25A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1C25
Dynodwyr
Cyfenwau	CDC25A, CDC25A2, cell division cycle 25A
Dynodwyr allanol	OMIM: 116947 HomoloGene: 1355 GeneCards: CDC25A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • protein tyrosine phosphatase activity • hydrolase activity • protein kinase binding • phosphoprotein phosphatase activity • chaperone binding Cydrannau o'r gell • cytoplasm • cytosol • intracellular anatomical structure • nucleoplasm • cnewyllyn cell Prosesau biolegol • regulation of cyclin-dependent protein serine/threonine kinase activity • cellular response to UV • GO:0016576 protein dephosphorylation • regulation of cell cycle • Cellraniad • G2/M transition of mitotic cell cycle • cell cycle • response to radiation • peptidyl-tyrosine dephosphorylation • cell population proliferation • protein deubiquitination • positive regulation of cell cycle G2/M phase transition • G1/S transition of mitotic cell cycle • positive regulation of G2/M transition of mitotic cell cycle • positive regulation of mitotic cell cycle • positive regulation of G2/MI transition of meiotic cell cycle Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	993	n/a
Ensembl	ENSG00000164045	n/a
UniProt	P30304	n/a
RefSeq (mRNA)	NM_001789 NM_201567	n/a
RefSeq (protein)	NP_001780 NP_963861	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CDC25A yw CDC25A a elwir hefyd yn Cell division cycle 25A, isoform CRA_a a Cell division cycle 25a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3p21.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CDC25A.

• CDC25A2

Llyfryddiaeth

• "Accumulation of cytoplasmic CDC25A in cutaneous squamous cell carcinoma leads to a dependency on CDC25A for cancer cell survival and tumor growth. ". Cancer Lett. 2017. PMID 28951130.
• "CyclinD-CDK4/6 complexes phosphorylate CDC25A and regulate its stability. ". Oncogene. 2017. PMID 28192398.
• "Phosphorylation of CDC25A on SER283 in late S/G2 by CDK/cyclin complexes accelerates mitotic entry. ". Cell Cycle. 2016. PMID 27580187.
• "Identification of key genes in hepatocellular carcinoma and validation of the candidate gene, cdc25a, using gene set enrichment analysis, meta-analysis and cross-species comparison. ". Mol Med Rep. 2016. PMID 26647881.
• "CDC25A-inhibitory RE derivatives bind to pocket adjacent to the catalytic site.". Mol Biosyst. 2013. PMID 23467652.