CDA

CDA
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1MQ0
Dynodwyr
Cyfenwau	CDA, CDD, cytidine deaminase
Dynodwyr allanol	OMIM: 123920 HomoloGene: 1352 GeneCards: CDA
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • nucleoside binding • cytidine deaminase activity • zinc ion binding • metal ion binding • GO:0001948, GO:0016582 protein binding • catalytic activity • identical protein binding • hydrolase activity Cydrannau o'r gell • cytosol • extracellular region • secretory granule lumen • tertiary granule lumen • ficolin-1-rich granule lumen Prosesau biolegol • cytosine metabolic process • pyrimidine nucleoside salvage • cell surface receptor signaling pathway • cytidine deamination • negative regulation of cell growth • pyrimidine-containing compound salvage • negative regulation of nucleotide metabolic process • protein homotetramerization • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	978	n/a
Ensembl	ENSG00000158825	n/a
UniProt	P32320	n/a
RefSeq (mRNA)	NM_001785	n/a
RefSeq (protein)	NP_001776	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CDA yw CDA a elwir hefyd yn Cytidine deaminase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p36.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CDA.

• CDD

Llyfryddiaeth

• "Cytidine Deaminase as a Molecular Predictor of Gemcitabine Response in Patients with Biliary Tract Cancer. ". Oncology. 2015. PMID 26418006.
• "Cytidine deaminase polymorphisms and worse treatment response in normal karyotype AML. ". J Hum Genet. 2015. PMID 26354033.
• "CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer. ". Nature. 2015. PMID 26200337.
• "Lethal toxicity after administration of azacytidine: implication of the cytidine deaminase-deficiency syndrome. ". Pharmacogenet Genomics. 2015. PMID 25850965.
• "Cytidine deaminase polymorphism predicts toxicity of gemcitabine-based chemotherapy.". Gene. 2015. PMID 25582275.