CD3D

CD3D
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1XIW
Dynodwyr
Cyfenwau	CD3D, CD3-DELTA, IMD19, T3D, CD3d molecule, CD3 delta subunit of T-cell receptor complex, CD3DELTA
Dynodwyr allanol	OMIM: 186790 HomoloGene: 585 GeneCards: CD3D
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001105 transcription coactivator activity • protein heterodimerization activity • transmembrane signaling receptor activity • protein homodimerization activity Cydrannau o'r gell • bilen • cytoplasm • alpha-beta T cell receptor complex • integral component of membrane • T cell receptor complex • clathrin-coated vesicle membrane • Cellbilen • external side of plasma membrane Prosesau biolegol • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • regulation of immune response • T cell receptor signaling pathway • T cell differentiation • positive thymic T cell selection • cell surface receptor signaling pathway • membrane organization • protein homooligomerization • adaptive immune response • immune system process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	915	n/a
Ensembl	ENSG00000167286	n/a
UniProt	P04234	n/a
RefSeq (mRNA)	NM_001040651 NM_000732	n/a
RefSeq (protein)	NP_000723 NP_001035741	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CD3D yw CD3D a elwir hefyd yn T-cell surface glycoprotein CD3 delta chain a CD3d molecule (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CD3D.

• T3D
• IMD19
• CD3-DELTA

Llyfryddiaeth

• "The respiratory presentation of severe combined immunodeficiency in two Mennonite children at a tertiary centre highlighting the importance of recognizing this pediatric emergency. ". Can Respir J. 2014. PMID 24288697.
• "A leaky mutation in CD3D differentially affects αβ and γδ T cells and leads to a Tαβ-Tγδ+B+NK+ human SCID. ". J Clin Invest. 2011. PMID 21926461.
• "Flow cytometric quantitation of natural killer cells and T lymphocytes expressing T-cell receptors alpha/beta and gamma/delta is not helpful in distinguishing benign from malignant body cavity effusions. ". Cytometry B Clin Cytom. 2009. PMID 18803280.
• "The T cell antigen receptor alpha and beta chains interact via distinct regions with CD3 chains. ". Eur J Immunol. 1994. PMID 8020575.
• "Composition of TCR-CD3 complex in human intestinal intraepithelial lymphocytes: lack of Fc epsilon RI gamma chain.". Int Immunol. 1995. PMID 7495730.