CD1A

CD1A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1ONQ, 1XZ0, 4X6C, 4X6D, 4X6E, 4X6F
Dynodwyr
Cyfenwau	CD1A, CD1, FCB6, HTA1, R4, T6, CD1a molecule
Dynodwyr allanol	OMIM: 188370 HomoloGene: 113556 GeneCards: CD1A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • beta-2-microglobulin binding • endogenous lipid antigen binding • GO:0001948, GO:0016582 protein binding • exogenous lipid antigen binding • lipopeptide binding Cydrannau o'r gell • integral component of membrane • membrane raft • endosome • integral component of plasma membrane • endosome membrane • bilen • Cellbilen • cell surface • extracellular space • external side of plasma membrane Prosesau biolegol • antigen processing and presentation, exogenous lipid antigen via MHC class Ib • adaptive immune response • immune system process • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • regulation of immune response • positive regulation of T cell mediated cytotoxicity • antigen processing and presentation, endogenous lipid antigen via MHC class Ib Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	909	n/a
Ensembl	ENSG00000158477	n/a
UniProt	P06126	n/a
RefSeq (mRNA)	NM_001763 NM_001320652	n/a
RefSeq (protein)	NP_001307581 NP_001754	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CD1A yw CD1A a elwir hefyd yn CD1a molecule (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q23.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CD1A.

• R4
• T6
• CD1
• FCB6
• HTA1

Llyfryddiaeth

• "Immunological profiling of patients with ulcerative colitis leads to identification of two inflammatory conditions and CD1a as a disease marker. ". J Transl Med. 2016. PMID 27809916.
• "CD1a on Langerhans cells controls inflammatory skin disease. ". Nat Immunol. 2016. PMID 27548435.
• "Expression of CD1a and Type-1 Polarization Are Dissociated in Human Monocyte-Derived Dendritic Cells. ". PLoS One. 2015. PMID 26460687.
• "Activation of human T cells by CD1 and self-lipids. ". Immunol Rev. 2015. PMID 26284469.
• "CD1a-positive dendritic cell density predicts disease-free survival in papillary thyroid carcinoma.". Pathol Res Pract. 2015. PMID 26073685.