CCL7

CCL7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1BO0, 1NCV, 4ZKC
Dynodwyr
Cyfenwau	CCL7, FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7, C-C motif chemokine ligand 7
Dynodwyr allanol	OMIM: 158106 HomoloGene: 4568 GeneCards: CCL7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • cytokine activity • heparin binding • chemokine activity • CCR1 chemokine receptor binding • GO:0001948, GO:0016582 protein binding • CCR2 chemokine receptor binding • CCR chemokine receptor binding Cydrannau o'r gell • extracellular region • extracellular space Prosesau biolegol • G protein-coupled receptor signaling pathway • monocyte chemotaxis • positive regulation of cell migration • positive regulation of natural killer cell chemotaxis • chemokine-mediated signaling pathway • cellular response to tumor necrosis factor • cell-cell signaling • eosinophil chemotaxis • cellular calcium ion homeostasis • neutrophil chemotaxis • chemotaxis • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • cytoskeleton organization • cellular response to interleukin-1 • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • positive regulation of ERK1 and ERK2 cascade • regulation of cell shape • cellular response to interferon-gamma • inflammatory response • GO:0072468 signal transduction • response to gamma radiation • cellular response to ethanol • regulation of signaling receptor activity • lymphocyte chemotaxis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6354	n/a
Ensembl	ENSG00000108688	n/a
UniProt	P80098	n/a
RefSeq (mRNA)	NM_006273	n/a
RefSeq (protein)	NP_006264	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CCL7 yw CCL7 a elwir hefyd yn C-C motif chemokine ligand 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CCL7.

• FIC
• MARC
• MCP3
• NC28
• MCP-3
• SCYA6
• SCYA7

Llyfryddiaeth

• "Apoptosis induced by desmethyl-lasiodiplodin is associated with upregulation of apoptotic genes and downregulation of monocyte chemotactic protein-3. ". Anticancer Drugs. 2013. PMID 23764760.
• "CC chemokine ligand 7 expression in liver metastasis of colorectal cancer. ". Oncol Rep. 2012. PMID 22614322.
• "Monocyte chemotactic protein-3 induces human coronary smooth muscle cell proliferation. ". Atherosclerosis. 2011. PMID 21536288.
• "MCP-3/CCL7 production by astrocytes: implications for SIV neuroinvasion and AIDS encephalitis. ". J Neurovirol. 2011. PMID 21279498.
• "Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7.". Int J Cancer. 2010. PMID 19937793.