CCL20

CCL20
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2JYO, 1M8A, 2HCI
Dynodwyr
Cyfenwau	CCL20, CKb4, Exodus, LARC, MIP-3-alpha, MIP-3a, MIP3A, SCYA20, ST38, chemokine (C-C motif) ligand 20, C-C motif chemokine ligand 20
Dynodwyr allanol	OMIM: 601960 HomoloGene: 3375 GeneCards: CCL20
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • cytokine activity • GO:0001948, GO:0016582 protein binding • CCR6 chemokine receptor binding • chemokine activity • CCR chemokine receptor binding Cydrannau o'r gell • extracellular region • intracellular anatomical structure • extracellular space Prosesau biolegol • monocyte chemotaxis • positive regulation of T cell migration • neutrophil chemotaxis • positive regulation of ERK1 and ERK2 cascade • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • positive regulation of nitric-oxide synthase biosynthetic process • defense response to bacterium • cell-cell signaling • lymphocyte chemotaxis • wound healing • cellular response to lipoteichoic acid • cellular response to tumor necrosis factor • cellular response to organic substance • chemokine-mediated signaling pathway • cellular response to interleukin-1 • cellular response to interferon-gamma • GO:0072468 signal transduction • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • cellular response to lipopolysaccharide • chemotaxis • calcium-mediated signaling using intracellular calcium source • cell chemotaxis • T cell migration • thymocyte migration • inflammatory response • antimicrobial humoral immune response mediated by antimicrobial peptide • regulation of signaling receptor activity • G protein-coupled receptor signaling pathway • cytokine-mediated signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6364	n/a
Ensembl	ENSG00000115009	n/a
UniProt	P78556	n/a
RefSeq (mRNA)	NM_004591 NM_001130046	n/a
RefSeq (protein)	NP_001123518 NP_004582	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CCL20 yw CCL20 a elwir hefyd yn C-C motif chemokine ligand 20 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q36.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CCL20.

• CKb4
• LARC
• ST38
• MIP3A
• Exodus
• MIP-3a
• SCYA20
• MIP-3-alpha

Llyfryddiaeth

• "CCL20 promotes migration and invasiveness of human cancerous breast epithelial cells in primary culture. ". Mol Carcinog. 2017. PMID 28618084.
• "CCL20 secreted from IgA1-stimulated human mesangial cells recruits inflammatory Th17 cells in IgA nephropathy. ". PLoS One. 2017. PMID 28552941.
• "Rhinovirus-bacteria coexposure synergistically induces CCL20 production from human bronchial epithelial cells. ". Am J Physiol Lung Cell Mol Physiol. 2017. PMID 28283475.
• "Role of CCL20 mediated immune cell recruitment in NF-κB mediated TRAIL resistance of pancreatic cancer. ". Biochim Biophys Acta. 2017. PMID 28188806.
• "Tumor-associated macrophage-derived CCL20 enhances the growth and metastasis of pancreatic cancer.". Acta Biochim Biophys Sin (Shanghai). 2016. PMID 27797715.