CCL11

CCL11
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1EOT, 2EOT, 2MPM
Dynodwyr
Cyfenwau	CCL11, SCYA11, C-C motif chemokine ligand 11
Dynodwyr allanol	OMIM: 601156 HomoloGene: 7929 GeneCards: CCL11
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • cytokine activity • GO:0001948, GO:0016582 protein binding • chemokine activity • CCR3 chemokine receptor binding • protein dimerization activity • receptor ligand activity • CCR chemokine receptor binding Cydrannau o'r gell • extracellular region • extracellular space • intracellular anatomical structure Prosesau biolegol • G protein-coupled receptor signaling pathway • positive regulation of endothelial cell proliferation • positive regulation of actin filament polymerization • response to interleukin-4 • branching involved in mammary gland duct morphogenesis • monocyte chemotaxis • actin filament organization • positive regulation of cell migration • chemokine-mediated signaling pathway • response to interleukin-13 • cellular response to tumor necrosis factor • response to virus • cellular calcium ion homeostasis • mast cell chemotaxis • neutrophil chemotaxis • positive regulation of angiogenesis • mammary duct terminal end bud growth • chemotaxis • protein phosphorylation • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • cell adhesion • cytoskeleton organization • cellular response to interleukin-1 • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • positive regulation of ERK1 and ERK2 cascade • regulation of cell shape • cellular response to interferon-gamma • lymphocyte chemotaxis • response to radiation • inflammatory response • chronic inflammatory response • GO:0072468 signal transduction • eosinophil chemotaxis • antimicrobial humoral immune response mediated by antimicrobial peptide • regulation of signaling receptor activity • cytokine-mediated signaling pathway • ERK1 and ERK2 cascade Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6356	n/a
Ensembl	ENSG00000172156	n/a
UniProt	P51671	n/a
RefSeq (mRNA)	NM_002986	n/a
RefSeq (protein)	NP_002977	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CCL11 yw CCL11 a elwir hefyd yn C-C motif chemokine ligand 11 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CCL11.

• SCYA11

Llyfryddiaeth

• "CCL11 is increased in the CNS in chronic traumatic encephalopathy but not in Alzheimer's disease. ". PLoS One. 2017. PMID 28950005.
• "Eotaxin Augments Calcification in Vascular Smooth Muscle Cells. ". J Cell Biochem. 2017. PMID 27681294.
• "The Relation between eNOS -786 C/T, 4 a/b, MMP-13 rs640198 G/T, Eotaxin 426 C/T, -384 A/G, and 67 G/A Polymorphisms and Long-Term Outcome in Patients with Coronary Artery Disease. ". Dis Markers. 2015. PMID 26491210.
• "Whole-genome sequencing suggests a chemokine gene cluster that modifies age at onset in familial Alzheimer's disease. ". Mol Psychiatry. 2015. PMID 26324103.
• "Is Eotaxin-1 a serum and urinary biomarker for prostate cancer detection and recurrence?". Prostate. 2015. PMID 26306920.