CANT1

CANT1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1S18, 1S1D, 2H2N, 2H2U
Dynodwyr
Cyfenwau	CANT1, DBQD, SCAN-1, SCAN1, SHAPY, DBQD1, calcium activated nucleotidase 1, EDM7
Dynodwyr allanol	OMIM: 613165 HomoloGene: 69460 GeneCards: CANT1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • uridine-diphosphatase activity • hydrolase activity • signal transducer activity • nucleoside-diphosphatase activity • metal ion binding • calcium ion binding • protein homodimerization activity • adenosine-diphosphatase activity • guanosine-diphosphatase activity • GO:0097382 pyrophosphatase activity Cydrannau o'r gell • integral component of membrane • Golgi cisterna membrane • Golgi apparatus • extracellular exosome • endoplasmic reticulum membrane • Reticwlwm endoplasmig • extracellular region • Cellbilen • bilen • specific granule lumen • tertiary granule lumen • ficolin-1-rich granule lumen Prosesau biolegol • positive regulation of I-kappaB kinase/NF-kappaB signaling • proteoglycan biosynthetic process • GO:0072468 signal transduction • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	124583	n/a
Ensembl	ENSG00000171302	n/a
UniProt	Q8WVQ1	n/a
RefSeq (mRNA)	NM_001159772 NM_001159773 NM_138793	n/a
RefSeq (protein)	NP_001153244 NP_001153245 NP_620148	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CANT1 yw CANT1 a elwir hefyd yn Soluble calcium-activated nucleotidase 1 a Calcium activated nucleotidase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q25.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CANT1.

• DBQD
• EDM7
• DBQD1
• SCAN1
• SHAPY
• SCAN-1

Llyfryddiaeth

• "The androgen-regulated Calcium-Activated Nucleotidase 1 (CANT1) is commonly overexpressed in prostate cancer and is tumor-biologically relevant in vitro. ". Am J Pathol. 2011. PMID 21435463.
• "A founder mutation of CANT1 common in Korean and Japanese Desbuquois dysplasia. ". J Hum Genet. 2011. PMID 21412251.
• "MED resulting from recessively inherited mutations in the gene encoding calcium-activated nucleotidase CANT1. ". Am J Med Genet A. 2017. PMID 28742282.
• "A novel CANT1 mutation in three Indian patients with Desbuquois dysplasia Kim type. ". Eur J Med Genet. 2015. PMID 25486376.
• "Desbuquois dysplasia type I and fetal hydrops due to novel mutations in the CANT1 gene.". Eur J Hum Genet. 2011. PMID 21654728.