CAMP

CAMP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4EYC, 2FBS, 2FBU, 2FCG, 2K6O
Dynodwyr
Cyfenwau	CAMP, IPR001894, CAP-18, CAP18, CRAMP, HSD26, gene FALL39, gene LL37, FALL39, LL37, FALL-39, cathelicidin antimicrobial peptide, Cathelicidins
Dynodwyr allanol	OMIM: 600474 HomoloGene: 110678 GeneCards: CAMP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • lipopolysaccharide binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • extracellular region • specific granule • extracellular exosome • extracellular space • intracellular anatomical structure • specific granule lumen • tertiary granule lumen Prosesau biolegol • defense response • innate immune response in mucosa • innate immune response • killing by host of symbiont cells • chronic inflammatory response • defense response to bacterium • antimicrobial humoral response • antimicrobial humoral immune response mediated by antimicrobial peptide • cytolysis by host of symbiont cells • GO:0051636 defense response to Gram-negative bacterium • GO:0051637 defense response to Gram-positive bacterium • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	820	n/a
Ensembl	ENSG00000164047	n/a
UniProt	P49913	n/a
RefSeq (mRNA)	NM_004345	n/a
RefSeq (protein)	NP_004336	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CAMP yw CAMP a elwir hefyd yn Cathelicidin antimicrobial peptide (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3p21.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CAMP.

• LL37
• CAP18
• CRAMP
• HSD26
• CAP-18
• FALL39
• FALL-39

Llyfryddiaeth

• "Cathelicidin LL37 Promotes Epithelial and Smooth-Muscle-Like Differentiation of Adipose-Derived Stem Cells through the Wnt/β-Catenin and NF-κB Pathways. ". Biochemistry (Mosc). 2017. PMID 29223160.
• "Is cathelicidin a novel marker of diabetic microangiopathy in patients with type 1 diabetes?". Clin Biochem. 2017. PMID 28964758.
• "Serum level of cathelicidin LL-37 in patients with active tuberculosis and other infectious diseases. ". J Biol Regul Homeost Agents. 2017. PMID 28956425.
• "Expression of human cathelicidin peptide LL-37 in inflammatory bowel disease. ". Clin Exp Immunol. 2018. PMID 28872665.
• "Carbon Nanoparticles Inhibit the Antimicrobial Activities of the Human Cathelicidin LL-37 through Structural Alteration.". J Immunol. 2017. PMID 28814602.