CAMK1

CAMK1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4FG7, 4FG8, 4FG9, 4FGB
Dynodwyr
Cyfenwau	CAMK1, CAMKI, calcium/calmodulin dependent protein kinase I, CaMKI-alpha, CaM kinase I alpha
Dynodwyr allanol	OMIM: 604998 HomoloGene: 117458 GeneCards: CAMK1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • protein kinase activity • kinase activity • protein serine/threonine kinase activity • GO:0001948, GO:0016582 protein binding • catalytic activity • ATP binding • calmodulin-dependent protein kinase activity • calmodulin binding Cydrannau o'r gell • cytoplasm • cnewyllyn cell • intracellular anatomical structure • GO:0097483, GO:0097481 postsynaptic density • glutamatergic synapse • cytosol Prosesau biolegol • cell differentiation • positive regulation of synapse structural plasticity • positive regulation of muscle cell differentiation • regulation of muscle cell differentiation • phosphorylation • positive regulation of syncytium formation by plasma membrane fusion • regulation of histone H3-K9 acetylation • negative regulation of protein binding • positive regulation of dendritic spine development • nervous system development • positive regulation of peptidyl-serine phosphorylation • positive regulation of protein serine/threonine kinase activity • positive regulation of protein acetylation • regulation of protein localization • positive regulation of protein export from nucleus • multicellular organism development • protein phosphorylation • nucleocytoplasmic transport • positive regulation of neuron projection development • cell cycle • metabolaeth • regulation of protein binding • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • GO:0072468 signal transduction • peptidyl-threonine phosphorylation • GO:0007243 intracellular signal transduction • GO:1904739 regulation of synapse organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8536	n/a
Ensembl	ENSG00000134072	n/a
UniProt	Q14012	n/a
RefSeq (mRNA)	NM_003656	n/a
RefSeq (protein)	NP_003647 NP_003647.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CAMK1 yw CAMK1 a elwir hefyd yn Calcium/calmodulin-dependent protein kinase I, isoform CRA_a a Calcium/calmodulin dependent protein kinase I (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3p25.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CAMK1.

• CAMKI

Llyfryddiaeth

• "Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIalpha pathway. ". Mol Pharmacol. 2008. PMID 18089838.
• "Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase. ". EMBO J. 1995. PMID 7641687.
• "CAMK1 phosphoinositide signal-mediated protein sorting and transport network in human hepatocellular carcinoma (HCC) by biocomputation. ". Cell Biochem Biophys. 2014. PMID 24825433.
• "Crystal structures of human CaMKIα reveal insights into the regulation mechanism of CaMKI. ". PLoS One. 2012. PMID 23028635.
• "Aldosterone producing adrenal adenomas are characterized by activation of calcium/calmodulin-dependent protein kinase (CaMK) dependent pathways.". Horm Metab Res. 2011. PMID 21249615.