CACYBP

CACYBP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1X5M, 2A25, 2A26
Dynodwyr
Cyfenwau	CACYBP, GIG5, S100A6BP, SIP, PNAS-107, calcyclin binding protein
Dynodwyr allanol	OMIM: 606186 HomoloGene: 7649 GeneCards: CACYBP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • protein homodimerization activity • protein domain specific binding • ubiquitin protein ligase binding • tubulin binding • S100 protein binding Cydrannau o'r gell • nuclear envelope lumen • extracellular exosome • beta-catenin destruction complex • cnewyllyn cell • nucleoplasm • neuron projection • cell body • cytoplasm • cytosol • SCF ubiquitin ligase complex Prosesau biolegol • cardiac muscle cell differentiation • positive regulation of DNA replication • GO:0010260 heneiddio • negative regulation of cell death • cellular response to calcium ion • heart development • response to growth hormone • cellular response to leukemia inhibitory factor Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	27101	n/a
Ensembl	ENSG00000116161	n/a
UniProt	Q9HB71	n/a
RefSeq (mRNA)	NM_014412 NM_001007214	n/a
RefSeq (protein)	NP_001007215 NP_055227	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CACYBP yw CACYBP a elwir hefyd yn Calcyclin binding protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q25.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CACYBP.

• SIP
• GIG5
• PNAS-107
• S100A6BP

Llyfryddiaeth

• "CacyBP/SIP protein is important for the proliferation of human glioma cells. ". IUBMB Life. 2014. PMID 24740456.
• "iTRAQ based quantitative proteomics approach validated the role of calcyclin binding protein (CacyBP) in promoting colorectal cancer metastasis. ". Mol Cell Proteomics. 2013. PMID 23543800.
• "CacyBP/SIP inhibits Doxourbicin-induced apoptosis of glioma cells due to activation of ERK1/2. ". IUBMB Life. 2016. PMID 26825673.
• "Expression and regulation of CacyBP/SIP in chronic lymphocytic leukemia cell balances of cell proliferation with apoptosis. ". J Cancer Res Clin Oncol. 2016. PMID 26603518.
• "CacyBP/SIP nuclear translocation induced by gastrin promotes gastric cancer cell proliferation.". World J Gastroenterol. 2014. PMID 25110433.