CA4

CA4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1ZNC, 3F7B, 3F7U, 3FW3
Dynodwyr
Cyfenwau	CA4, CAIV, Car4, RP17, carbonic anhydrase 4
Dynodwyr allanol	OMIM: 114760 HomoloGene: 20183 GeneCards: CA4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • zinc ion binding • metal ion binding • GO:0001948, GO:0016582 protein binding • lyase activity • carbonate dehydratase activity • carbonic anhydrase Cydrannau o'r gell • rough endoplasmic reticulum • Golgi apparatus • bilen • secretory granule membrane • anchored component of plasma membrane • Cellbilen • transport vesicle membrane • cell surface • brush border membrane • trans-Golgi network • basolateral plasma membrane • apical plasma membrane • anchored component of external side of plasma membrane • perinuclear region of cytoplasm • anchored component of membrane • extracellular exosome • endoplasmic reticulum-Golgi intermediate compartment Prosesau biolegol • one-carbon metabolic process • bicarbonate transport • metabolaeth Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	762	n/a
Ensembl	ENSG00000167434	n/a
UniProt	P22748	n/a
RefSeq (mRNA)	NM_000717	n/a
RefSeq (protein)	NP_000708	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CA4 yw CA4 a elwir hefyd yn Carbonic anhydrase 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q23.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CA4.

• CAIV
• Car4
• RP17

Llyfryddiaeth

• "Membrane associated carbonic anhydrase IV (CA IV): a personal and historical perspective. ". Subcell Biochem. 2014. PMID 24146379.
• "Carbonic anhydrase VI exon 2 genetic polymorphism in Turkish subjects with low caries experience (preliminary study). ". In Vivo. 2011. PMID 22021688.
• "Cell-specific differences in the processing of the R14W CAIV mutant associated with retinitis pigmentosa 17. ". J Cell Biochem. 2010. PMID 20626030.
• "Screening for the carbonic anhydrase IV gene mutations in Chinese retinitis pigmentosa patients. ". Curr Eye Res. 2010. PMID 20450258.
• "Pathogenesis of retinitis pigmentosa associated with apoptosis-inducing mutations in carbonic anhydrase IV.". Proc Natl Acad Sci U S A. 2009. PMID 19211803.