C1QBP

C1QBP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1P32, 3RPX
Dynodwyr
Cyfenwau	C1QBP, GHABP1, SF2p32, gC1Q-R, gC1qR, p32, complement component 1, q subcomponent binding protein, complement C1q binding protein, COXPD33, SF2AP32
Dynodwyr allanol	OMIM: 601269 HomoloGene: 31023 GeneCards: C1QBP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001106 transcription corepressor activity • transcription factor binding • GO:0001948, GO:0016582 protein binding • hyaluronic acid binding • kininogen binding • mitochondrial ribosome binding • mRNA binding • protein kinase C binding • complement component C1q complex binding • adrenergic receptor binding • translation activator activity Cydrannau o'r gell • cytosol • extracellular region • cell surface • mitochondrial matrix • nucleolus • cytoplasm • bilen • mitocondria • cnewyllyn cell • extracellular space • Cellbilen • presynaptic active zone • presynapse • glutamatergic synapse • GABA-ergic synapse Prosesau biolegol • blood coagulation, intrinsic pathway • positive regulation of mitochondrial translation • negative regulation of interferon-gamma production • positive regulation of protein kinase B signaling • negative regulation of MDA-5 signaling pathway • GO:0009373 regulation of transcription, DNA-templated • adaptive immune response • ribosome biogenesis • negative regulation of defense response to virus • immune system process • mRNA processing • GO:1901227 negative regulation of transcription by RNA polymerase II • transcription, DNA-templated • positive regulation of trophoblast cell migration • positive regulation of substrate adhesion-dependent cell spreading • mature ribosome assembly • negative regulation of mRNA splicing, via spliceosome • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • RNA splicing • positive regulation of neutrophil chemotaxis • complement activation, classical pathway • positive regulation of apoptotic process • phosphatidylinositol 3-kinase signaling • innate immune response • GO:0022415 viral process • positive regulation of dendritic cell chemotaxis • regulation of complement activation • negative regulation of RIG-I signaling pathway • positive regulation of cell adhesion • negative regulation of interleukin-12 production • GO:0097285 apoptotic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	708	n/a
Ensembl	ENSG00000108561	n/a
UniProt	Q07021	n/a
RefSeq (mRNA)	NM_001212	n/a
RefSeq (protein)	NP_001203	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn C1QBP yw C1QBP a elwir hefyd yn Complement C1q binding protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17p13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn C1QBP.

• p32
• HABP1
• gC1qR
• GC1QBP
• SF2p32
• gC1Q-R
• COXPD33

Llyfryddiaeth

• "Biallelic C1QBP Mutations Cause Severe Neonatal-, Childhood-, or Later-Onset Cardiomyopathy Associated with Combined Respiratory-Chain Deficiencies. ". Am J Hum Genet. 2017. PMID 28942965.
• "Mitochondrial protein p32/HAPB1/gC1qR/C1qbp is required for efficient respiratory syncytial virus production. ". Biochem Biophys Res Commun. 2017. PMID 28576489.
• "Increased breast cancer risk with HABP1/p32/gC1qR genetic polymorphism rs2285747 and its upregulation in northern Chinese women. ". Oncotarget. 2017. PMID 28108744.
• "Hyaluronic acid binding protein 1 overexpression is an indicator for disease-free survival in cervical cancer. ". Int J Clin Oncol. 2017. PMID 28039537.
• "Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria.". PLoS Pathog. 2016. PMID 27835682.