C1QA

C1QA
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1PK6, 2JG8, 2JG9, 2WNU, 2WNV, 5HZF, 5HKJ
Dynodwyr
Cyfenwau	C1QA, complement C1q A chain
Dynodwyr allanol	OMIM: 120550 HomoloGene: 7249 GeneCards: C1QA
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • serine-type endopeptidase activity • amyloid-beta binding Cydrannau o'r gell • extracellular region • collagen • complement component C1 complex • collagen-containing extracellular matrix • synapse • postsynapse • amyloid-beta complex Prosesau biolegol • immune system process • complement activation • cell-cell signaling • complement activation, classical pathway • response to iron ion • innate immune response • proteolysis • regulation of complement activation • GO:0010260 heneiddio • neuron remodeling • synapse organization • positive regulation of astrocyte activation • synapse pruning • complement-mediated synapse pruning • vertebrate eye-specific patterning • positive regulation of neuron death • positive regulation of microglial cell activation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	712	n/a
Ensembl	ENSG00000173372	n/a
UniProt	P02745	n/a
RefSeq (mRNA)	NM_015991 NM_001347465 NM_001347466	n/a
RefSeq (protein)	NP_001334394 NP_001334395 NP_057075	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn C1QA yw C1QA a elwir hefyd yn Complement C1q A chain (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p36.12.

Llyfryddiaeth

• "C1q: A fresh look upon an old molecule. ". Mol Immunol. 2017. PMID 28601358.
• "Association between C1q gene polymorphisms and autoimmune thyroid diseases. ". Arch Endocrinol Metab. 2017. PMID 28225862.
• "The production and secretion of complement component C1q by human mast cells. ". Mol Immunol. 2016. PMID 27648858.
• "Anti-C1q autoantibodies from patients with systemic lupus erythematosus induce C1q production by macrophages. ". J Leukoc Biol. 2017. PMID 27630215.
• "Complement is activated in progressive multiple sclerosis cortical grey matter lesions.". J Neuroinflammation. 2016. PMID 27333900.