BST1

BST1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1ISF, 1ISG, 1ISH, 1ISI, 1ISJ, 1ISM
Dynodwyr
Cyfenwau	BST1, CD157, bone marrow stromal cell antigen 1
Dynodwyr allanol	OMIM: 600387 HomoloGene: 3198 GeneCards: BST1
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• NAD(P)+ nucleosidase activity; • transferase activity; • hydrolase activity; • NAD+ nucleotidase, cyclic ADP-ribose generating; • ADP-ribosyl cyclase activity; • cyclic ADP-ribose hydrolase; • NAD+ nucleosidase activity; • phosphorus-oxygen lyase activity;
Cydrannau o'r gell	• anchored component of membrane; • extracellular exosome; • bilen; • uropod; • extracellular region; • integrin complex; • extrinsic component of membrane; • specific granule membrane; • Cellbilen;
Prosesau biolegol	• regulation of cell-matrix adhesion; • regulation of cellular extravasation; • C-terminal protein lipidation; • humoral immune response; • GO:0072468 signal transduction; • positive regulation of cell population proliferation; • NAD metabolic process; • regulation of actin cytoskeleton organization; • neutrophil degranulation; • regulation of inflammatory response; • regulation of peptidyl-tyrosine phosphorylation; • regulation of calcium-mediated signaling; • regulation of neutrophil chemotaxis; • regulation of superoxide metabolic process; • regulation of integrin-mediated signaling pathway; • positive regulation of B cell proliferation;
	Sources:Amigo / QuickGO
Orthologau
	683
	n/a
	ENSG00000109743
	n/a
	Q10588
	n/a
	NM_004334
	n/a
	NP_004325
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BST1 yw BST1 a elwir hefyd yn ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 a Bone marrow stromal cell antigen 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4p15.32.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BST1.

CD157

Llyfryddiaeth

"Association between bone marrow stromal cell antigen 1 gene polymorphisms and the susceptibility to Parkinson's disease: a meta-analysis. ". Neurosci Lett. 2015. PMID 25986899.
"A pre-steady state and steady state kinetic analysis of the N-ribosyl hydrolase activity of hCD157. ". Arch Biochem Biophys. 2014. PMID 25250980.
"BST1 rs11724635 interacts with environmental factors to increase the risk of Parkinson's disease in a Taiwanese population. ". Parkinsonism Relat Disord. 2014. PMID 24342025.
"Exonic sequencing revealed no causative mutation in the BST1 gene in patients with Parkinson's disease. ". Neurobiol Aging. 2013. PMID 23827523.
"Lack of association between BST1 polymorphisms and sporadic Parkinson's disease in a Japanese population.". J Neurol Sci. 2012. PMID 23026536.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] BST1 - Cronfa NCBI

[1]

[2]