BRD3

BRD3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2E7N, 2NXB, 2OO1, 2YW5, 3S91, 3S92, 5HFR, 5A7C, 5HJC
Dynodwyr
Cyfenwau	BRD3, ORFX, RING3L, bromodomain containing 3
Dynodwyr allanol	OMIM: 601541 HomoloGene: 81801 GeneCards: BRD3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • chromatin binding • lysine-acetylated histone binding Cydrannau o'r gell • cnewyllyn cell Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • transcription, DNA-templated • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8019	n/a
Ensembl	ENSG00000169925	n/a
UniProt	Q15059	n/a
RefSeq (mRNA)	NM_007371	n/a
RefSeq (protein)	NP_031397 NP_031397.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BRD3 yw BRD3 a elwir hefyd yn Bromodomain containing 3 a Bromodomain containing 3, isoform CRA_a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9q34.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BRD3.

• ORFX
• RING3L

Llyfryddiaeth

• "Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3. ". Mol Cell Biol. 2011. PMID 21555453.
• "Chromosomal localization, gene structure and transcription pattern of the ORFX gene, a homologue of the MHC-linked RING3 gene. ". Gene. 1997. PMID 9373153.
• "The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis. ". Nat Commun. 2016. PMID 26947130.
• "Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function. ". Cell Rep. 2014. PMID 24565511.
• "Detection of the genes induced in activated lymphocytes by modified differential display.". J Investig Allergol Clin Immunol. 2002. PMID 12371535.