BRD2

BRD2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1X0J, 2DVQ, 2DVR, 2DVS, 2DVV, 2E3K, 2G4A, 2YDW, 2YEK, 3AQA, 3ONI, 4A9E, 4A9F, 4A9H, 4A9I, 4A9J, 4A9M, 4A9N, 4A9O, 4AKN, 4ALG, 4ALH, 4J1P, 4MR5, 4MR6, 4QEU, 4QEV, 4QEW, 4UYF, 4UYG, 4UYH, 5BT5, 5DFD, 5HEM, 5DFB, 5HEL, 5HFQ, 5HEN, 5DFC, 5IG6, 5IBN, 5DW1
Dynodwyr
Cyfenwau	BRD2, D6S113E, FSH, FSRG1, NAT, RING3, RNF3, O27.1.1, bromodomain containing 2, BRD2-IT1
Dynodwyr allanol	OMIM: 601540 HomoloGene: 74540 GeneCards: BRD2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • chromatin binding • GO:0001948, GO:0016582 protein binding • lysine-acetylated histone binding Cydrannau o'r gell • cytoplasm • cnewyllyn cell • nucleoplasm • nuclear speck Prosesau biolegol • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • nucleosome assembly • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • spermatogenesis • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization • GO:0022415 viral process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6046	n/a
Ensembl	ENSG00000215077 ENSG00000234507 ENSG00000230678 ENSG00000204256 ENSG00000235307 ENSG00000236227 ENSG00000234704	n/a
UniProt	P25440	n/a
RefSeq (mRNA)	NM_001113182 NM_001199455 NM_001199456 NM_001291986 NM_005104	n/a
RefSeq (protein)	NP_001106653 NP_001186384 NP_001186385 NP_001278915 NP_005095	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BRD2 yw BRD2 a elwir hefyd yn Bromodomain-containing protein 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6p21.32.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BRD2.

• FSH
• NAT
• RNF3
• FSRG1
• RING3
• D6S113E
• O27.1.1
• BRD2-IT1

Llyfryddiaeth

• "Structural basis for acetylated histone H4 recognition by the human BRD2 bromodomain. ". J Biol Chem. 2010. PMID 20048151.
• "Association analysis of BRD2 (RING3) and epilepsy in a Dutch population. ". Epilepsia. 2007. PMID 17999746.
• "RNF43 mutation frequently occurs with GNAS mutation and mucin hypersecretion in intraductal papillary neoplasms of the bile duct. ". Histopathology. 2017. PMID 27864998.
• "The C-terminal domain of Brd2 is important for chromatin interaction and regulation of transcription and alternative splicing. ". Mol Biol Cell. 2013. PMID 24048450.
• "Bromodomain-containing protein 2 gene in photosensitive epilepsy.". Seizure. 2012. PMID 22766109.