BIRC7

BIRC7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1OXN, 1OXQ, 1OY7, 1TW6, 2I3H, 2I3I, 3F7G, 3F7H, 3F7I, 3GT9, 3GTA, 3UW5, 4AUQ
Dynodwyr
Cyfenwau	BIRC7, KIAP, LIVIN, ML-IAP, MLIAP, RNF50, baculoviral IAP repeat containing 7
Dynodwyr allanol	OMIM: 605737 HomoloGene: 51405 GeneCards: BIRC7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peptidase inhibitor activity • cysteine-type endopeptidase inhibitor activity • metal ion binding • GO:0050372 ubiquitin-protein transferase activity • GO:0001948, GO:0016582 protein binding • enzyme binding • transferase activity • cysteine-type endopeptidase inhibitor activity involved in apoptotic process • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity Cydrannau o'r gell • cytoplasm • Golgi apparatus • cnewyllyn cell • microtubule organizing center • cytosol Prosesau biolegol • negative regulation of peptidase activity • inhibition of cysteine-type endopeptidase activity involved in apoptotic process • negative regulation of apoptotic process • regulation of natural killer cell apoptotic process • mitotic spindle assembly • regulation of cell population proliferation • regulation of signal transduction • protein ubiquitination • GO:0097285 apoptotic process • positive regulation of protein ubiquitination • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	79444	n/a
Ensembl	ENSG00000101197	n/a
UniProt	Q96CA5	n/a
RefSeq (mRNA)	NM_139317 NM_022161	n/a
RefSeq (protein)	NP_071444 NP_647478	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BIRC7 yw BIRC7 a elwir hefyd yn Baculoviral IAP repeat containing 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 20, band 20q13.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BIRC7.

• KIAP
• LIVIN
• MLIAP
• RNF50
• ML-IAP

Llyfryddiaeth

• "Inhibition of livin expression suppresses cell proliferation and enhances chemosensitivity to cisplatin in human lung adenocarcinoma cells. ". Mol Med Rep. 2015. PMID 25695324.
• "Research progress on the livin gene and osteosarcomas. ". Asian Pac J Cancer Prev. 2014. PMID 25374170.
• "Single-chain antibody-delivered Livin siRNA inhibits human malignant melanoma growth in vitro and in vivo. ". Tumour Biol. 2017. PMID 28459204.
• "Silencing Livin induces apoptotic and autophagic cell death, increasing chemotherapeutic sensitivity to cisplatin of renal carcinoma cells. ". Tumour Biol. 2016. PMID 27677286.
• "Livin enhances tumorigenesis by regulating the mitogen-activated protein kinase signaling pathway in human hypopharyngeal squamous cell carcinoma.". Mol Med Rep. 2016. PMID 27175933.