BCKDK

BCKDK
Dynodwyr
Cyfenwau	BCKDK, BCKDKD, BDK, branched chain ketoacid dehydrogenase kinase, branched chain keto acid dehydrogenase kinase
Dynodwyr allanol	OMIM: 614901 HomoloGene: 37642 GeneCards: BCKDK
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • protein serine/threonine kinase activity • protein kinase activity • transferase activity, transferring phosphorus-containing groups • GO:0001948, GO:0016582 protein binding • ATP binding • kinase activity • [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity] Cydrannau o'r gell • mitochondrial matrix • mitochondrial alpha-ketoglutarate dehydrogenase complex • mitocondria Prosesau biolegol • protein phosphorylation • cellular amino acid catabolic process • branched-chain amino acid catabolic process • phosphorylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10295	n/a
Ensembl	ENSG00000103507	n/a
UniProt	O14874	n/a
RefSeq (mRNA)	NM_005881 NM_001122957 NM_001271926	n/a
RefSeq (protein)	NP_001116429 NP_001258855 NP_005872 NP_005872.2	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BCKDK yw BCKDK a elwir hefyd yn Branched chain ketoacid dehydrogenase kinase, isoform CRA_b a Branched chain ketoacid dehydrogenase kinase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p11.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BCKDK.

• BDK
• BCKDKD

Llyfryddiaeth

• "Tissue-specific translation of murine branched-chain alpha-ketoacid dehydrogenase kinase mRNA is dependent upon an upstream open reading frame in the 5'-untranslated region. ". J Biol Chem. 2004. PMID 15302860.
• "Branched-chain alpha-ketoacid dehydrogenase kinase. Molecular cloning, expression, and sequence similarity with histidine protein kinases. ". J Biol Chem. 1992. PMID 1377677.
• "Two novel mutations in the BCKDK (branched-chain keto-acid dehydrogenase kinase) gene are responsible for a neurobehavioral deficit in two pediatric unrelated patients. ". Hum Mutat. 2014. PMID 24449431.
• "Regulation of the branched-chain alpha-ketoacid dehydrogenase and elucidation of a molecular basis for maple syrup urine disease. ". Adv Enzyme Regul. 1990. PMID 2403034.
• "The plasma levels of CST and BCKDK in patients with sepsis.". Peptides. 2016. PMID 27773658.