BAZ1B

BAZ1B
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1F62
Dynodwyr
Cyfenwau	BAZ1B, WBSCR10, WBSCR9, WSTF, bromodomain adjacent to zinc finger domain 1B
Dynodwyr allanol	OMIM: 605681 HomoloGene: 22651 GeneCards: BAZ1B
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • histone kinase activity • GO:0031493 histone binding • non-membrane spanning protein tyrosine kinase activity • metal ion binding • kinase activity • GO:0001948, GO:0016582 protein binding • protein tyrosine kinase activity • ATP binding • zinc ion binding Cydrannau o'r gell • pericentric heterochromatin • nuclear replication fork • nucleoplasm • condensed chromosome • cnewyllyn cell • nuclear body Prosesau biolegol • epigenetic maintenance of chromatin in transcription-competent conformation • chromatin remodeling • phosphorylation • transcription, DNA-templated • cellular response to DNA damage stimulus • peptidyl-tyrosine phosphorylation • GO:0009373 regulation of transcription, DNA-templated • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9031	n/a
Ensembl	ENSG00000009954	n/a
UniProt	Q9UIG0	n/a
RefSeq (mRNA)	NM_023005 NM_032408 NM_001370402	n/a
RefSeq (protein)	NP_115784 NP_001357331	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BAZ1B yw BAZ1B a elwir hefyd yn Bromodomain adjacent to zinc finger domain 1B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7q11.23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BAZ1B.

• WSTF
• WBSCR9
• WBSCR10

Llyfryddiaeth

• "Structure of the PHD zinc finger from human Williams-Beuren syndrome transcription factor. ". J Mol Biol. 2000. PMID 11124022.
• "A novel human gene, WSTF, is deleted in Williams syndrome. ". Genomics. 1998. PMID 9828126.
• "WSTF promotes proliferation and invasion of lung cancer cells by inducing EMT via PI3K/Akt and IL-6/STAT3 signaling pathways. ". Cell Signal. 2016. PMID 27449264.
• "Haploinsufficiency of BAZ1B contributes to Williams syndrome through transcriptional dysregulation of neurodevelopmental pathways. ". Hum Mol Genet. 2016. PMID 26755828.
• "WSTF does it all: a multifunctional protein in transcription, repair, and replication.". Biochem Cell Biol. 2011. PMID 21326359.