BANF1

BANF1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1QCK, 2ODG, 1CI4, 2BZF, 2EZY, 2EZZ, 2EZX
Dynodwyr
Cyfenwau	BANF1, BAF, BCRP1, D14S1460, NGPS, Barrier to autointegration factor 1, BAF nuclear assembly factor 1
Dynodwyr allanol	OMIM: 603811 HomoloGene: 2866 GeneCards: BANF1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • GO:0001948, GO:0016582 protein binding • protein C-terminus binding • enzyme binding • protein homodimerization activity • protein N-terminus binding • LEM domain binding • identical protein binding Cydrannau o'r gell • cytoplasm • extracellular exosome • condensed chromosome • cnewyllyn cell • Cromosom • nucleoplasm • cytosol • nuclear envelope Prosesau biolegol • mitotic nuclear membrane reassembly • response to virus • mitotic nuclear membrane disassembly • DNA integration • establishment of integrated proviral latency • GO:0022415 viral process • nuclear transport • negative regulation of viral genome replication • chromosome segregation • chromosome condensation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8815	n/a
Ensembl	ENSG00000175334	n/a
UniProt	O75531	n/a
RefSeq (mRNA)	NM_003860 NM_001143985	n/a
RefSeq (protein)	NP_001137457 NP_003851	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BANF1 yw BANF1 a elwir hefyd yn Barrier to autointegration factor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q13.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BANF1.

• BAF
• NGPS
• BCRP1
• D14S1460

Llyfryddiaeth

• "Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation. ". BMC Mol Biol. 2014. PMID 25495845.
• "Cell- and virus-mediated regulation of the barrier-to-autointegration factor's phosphorylation state controls its DNA binding, dimerization, subcellular localization, and antipoxviral activity. ". J Virol. 2014. PMID 24600006.
• "VRK2A is an A-type lamin-dependent nuclear envelope kinase that phosphorylates BAF. ". Mol Biol Cell. 2017. PMID 28637768.
• "The Barrier to Autointegration Factor: Interlocking Antiviral Defense with Genome Maintenance. ". J Virol. 2016. PMID 26842478.
• "BAF is a cytosolic DNA sensor that leads to exogenous DNA avoiding autophagy.". Proc Natl Acad Sci U S A. 2015. PMID 25991860.