BAG5

BAG5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2D9D, 3A8Y
Dynodwyr
Cyfenwau	BAG5, BAG-5, BCL2 associated athanogene 5, BAG cochaperone 5, CMD2F
Dynodwyr allanol	OMIM: 603885 HomoloGene: 3584 GeneCards: BAG5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • chaperone binding • GO:0001948, GO:0016582 protein binding • protein kinase binding • ubiquitin protein ligase binding • adenyl-nucleotide exchange factor activity Cydrannau o'r gell • cytosol • bilen • mitocondria • inclusion body • perinuclear region of cytoplasm • cnewyllyn cell Prosesau biolegol • neuron death • negative regulation of neuron projection development • Golgi organization • regulation of inclusion body assembly • negative regulation of protein ubiquitination • protein folding • negative regulation of ubiquitin-protein transferase activity • negative regulation of proteasomal ubiquitin-dependent protein catabolic process • regulation of cellular response to heat • negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway • negative regulation of protein refolding • regulation of ubiquitin-protein transferase activity • protein stabilization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9529	n/a
Ensembl	ENSG00000166170	n/a
UniProt	Q9UL15	n/a
RefSeq (mRNA)	NM_004873 NM_001015048 NM_001015049	n/a
RefSeq (protein)	NP_001015048 NP_001015049 NP_004864	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BAG5 yw BAG5 a elwir hefyd yn BCL2 associated athanogene 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 14, band 14q32.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BAG5.

• BAG-5

Llyfryddiaeth

• "MicroRNA-127 is aberrantly downregulated and acted as a functional tumor suppressor in human pancreatic cancer. ". Tumour Biol. 2016. PMID 27571739.
• "The BAG2 and BAG5 proteins inhibit the ubiquitination of pathogenic ataxin3-80Q. ". Int J Neurosci. 2015. PMID 25006867.
• "Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis. ". BMC Cancer. 2013. PMID 23448667.
• "GrpE-like regulation of the hsc70 chaperone by the anti-apoptotic protein BAG-1. ". EMBO J. 1997. PMID 9321400.
• "MicroRNA-127-3p acts as a tumor suppressor in epithelial ovarian cancer by regulating the BAG5 gene.". Oncol Rep. 2016. PMID 27571744.