BAG1

BAG1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1HX1, 1WXV, 3FZF, 3FZH, 3FZK, 3FZL, 3FZM, 3LDQ, 3M3Z
Dynodwyr
Cyfenwau	BAG1, BAG-1, HAP, RAP46, BCL2 associated athanogene 1, BAG cochaperone 1
Dynodwyr allanol	OMIM: 601497 HomoloGene: 3190 GeneCards: BAG1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • chaperone binding • GO:0001948, GO:0016582 protein binding • adenyl-nucleotide exchange factor activity • ubiquitin protein ligase binding Cydrannau o'r gell • cytoplasm • cytosol • cnewyllyn cell Prosesau biolegol • regulation of cellular response to heat • cell surface receptor signaling pathway • negative regulation of apoptotic process • GO:0097285 apoptotic process • GO:0048552 regulation of catalytic activity • chaperone cofactor-dependent protein refolding Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	573	n/a
Ensembl	ENSG00000107262	n/a
UniProt	Q99933	n/a
RefSeq (mRNA)	NM_004323 NM_001172415 NM_001349286 NM_001349299	n/a
RefSeq (protein)	NP_001165886 NP_004314 NP_001336215 NP_001336228	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BAG1 yw BAG1 a elwir hefyd yn BAG family molecular chaperone regulator 1 a BCL2 associated athanogene 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BAG1.

• HAP
• BAG-1
• RAP46

Llyfryddiaeth

• "BAG-1/SODD, HSP70, and HSP90 are potential prognostic markers of poor survival in node-negative breast carcinoma. ". Hum Pathol. 2016. PMID 27038683.
• "Human cytomegalovirus inhibits apoptosis involving upregulation of the antiapoptotic protein Bag-1. ". J Med Virol. 2015. PMID 26087710.
• "MiR-138 Suppresses Cell Proliferation by Targeting Bag-1 in Gallbladder Carcinoma. ". PLoS One. 2015. PMID 25962180.
• "Expression of BAG-1 is closely related to cell differentiation and TNM stage in esophageal cancer and its downregulation inhibits the proliferation and invasion of human esophageal carcinoma cells. ". Oncol Rep. 2014. PMID 25069471.
• "Expression and role of BAG-1 in eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps.". Inflammation. 2014. PMID 24830325.