BACH2

BACH2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3OHU, 3OHV
Dynodwyr
Cyfenwau	BACH2, BTBD25, BTB domain and CNC homolog 2, IMD60
Dynodwyr allanol	OMIM: 605394 HomoloGene: 7240 GeneCards: BACH2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0050372 ubiquitin-protein transferase activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cytoplasm • Cul3-RING ubiquitin ligase complex • cnewyllyn cell • cytosol Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • GO:1901227 negative regulation of transcription by RNA polymerase II • transcription by RNA polymerase II • transcription, DNA-templated • protein ubiquitination • import into nucleus Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	60468	n/a
Ensembl	ENSG00000112182	n/a
UniProt	Q9BYV9	n/a
RefSeq (mRNA)	NM_001170794 NM_021813	n/a
RefSeq (protein)	NP_001164265 NP_068585	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn BACH2 yw BACH2 a elwir hefyd yn BTB domain and CNC homolog 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6q15.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn BACH2.

• BTBD25

Llyfryddiaeth

• "Charge-state-distribution analysis of Bach2 intrinsically disordered heme binding region. ". J Biochem. 2016. PMID 27206783.
• "No association between Bach2 gene polymorphisms with Vogt-Koyanagi-Harada syndrome (VKH) and Behcet's disease (BD) in a Chinese Han population. ". Br J Ophthalmol. 2015. PMID 25873652.
• "BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency. ". Nat Immunol. 2017. PMID 28530713.
• "Frequent downregulation of BTB and CNC homology 2 expression in Epstein-Barr virus-positive diffuse large B-cell lymphoma. ". Cancer Sci. 2017. PMID 28256087.
• "A Variant in the BACH2 Gene Is Associated With Susceptibility to Autoimmune Addison's Disease in Humans.". J Clin Endocrinol Metab. 2016. PMID 27680876.