AZU1

AZU1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1A7S, 1AE5, 1FY1, 1FY3
Dynodwyr
Cyfenwau	AZU1, AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC, hHBP, azurocidin 1
Dynodwyr allanol	OMIM: 162815 HomoloGene: 74404 GeneCards: AZU1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • heparin binding • GO:0070122 peptidase activity • GO:0001948, GO:0016582 protein binding • heparan sulfate proteoglycan binding • toxic substance binding • serine-type endopeptidase activity Cydrannau o'r gell • bilen • azurophil granule • azurophil granule membrane • extracellular exosome • extrinsic component of membrane • extracellular region • extracellular space • azurophil granule lumen Prosesau biolegol • positive regulation of MHC class II biosynthetic process • positive regulation of phagocytosis • negative regulation of apoptotic process • protein kinase C signaling • microglial cell activation • proteolysis • induction of positive chemotaxis • monocyte activation • chemotaxis • regulation of vascular permeability • GO:1901313 positive regulation of gene expression • macrophage chemotaxis • protein kinase C-activating G protein-coupled receptor signaling pathway • defense response to bacterium • positive regulation of peptidyl-threonine phosphorylation • neutrophil-mediated killing of bacterium • GO:0051636 defense response to Gram-negative bacterium • cell chemotaxis • cellular extravasation • inflammatory response • calcium-mediated signaling using intracellular calcium source • glial cell migration • positive regulation of cell adhesion • positive regulation of protein kinase activity • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	566	n/a
Ensembl	ENSG00000278624 ENSG00000172232	n/a
UniProt	P20160	n/a
RefSeq (mRNA)	NM_001700	n/a
RefSeq (protein)	NP_001691	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn AZU1 yw AZU1 a elwir hefyd yn Azurocidin 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AZU1.

• AZU
• HBP
• NAZC
• hHBP
• AZAMP
• CAP37
• HUMAZUR

Llyfryddiaeth

• "The antimicrobial protein, CAP37, is upregulated in pyramidal neurons during Alzheimer's disease. ". Histochem Cell Biol. 2015. PMID 26170148.
• "A multifunctional peptide based on the neutrophil immune defense molecule, CAP37, has antibacterial and wound-healing properties. ". J Leukoc Biol. 2015. PMID 25412625.
• "Increased plasma levels of heparin-binding protein in patients with acute respiratory distress syndrome. ". Crit Care. 2013. PMID 23883488.
• "Azurocidin levels in maternal serum in the first trimester can predict preterm prelabor rupture of membranes. ". J Matern Fetal Neonatal Med. 2014. PMID 23808364.
• "Increased plasma levels of heparin-binding protein in patients with shock: a prospective, cohort study.". Inflamm Res. 2012. PMID 22207392.