ARIH1

ARIH1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WD2, 2M9Y, 4KBL, 4KC9
Dynodwyr
Cyfenwau	ARIH1, ARI, HARI, HHARI, UBCH7BP, ariadne RBR E3 ubiquitin protein ligase 1
Dynodwyr allanol	OMIM: 605624 HomoloGene: 111871 GeneCards: ARIH1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • ubiquitin-like protein transferase activity • GO:0001948, GO:0016582 protein binding • metal ion binding • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • ubiquitin protein ligase binding • GO:0050372 ubiquitin-protein transferase activity • transferase activity • ubiquitin conjugating enzyme binding • zinc ion binding Cydrannau o'r gell • cytoplasm • ubiquitin ligase complex • cytosol • cnewyllyn cell • Cajal body • nuclear body • SCF ubiquitin ligase complex • Cul2-RING ubiquitin ligase complex • Cul3-RING ubiquitin ligase complex • Cul4A-RING E3 ubiquitin ligase complex • Lewy body Prosesau biolegol • protein polyubiquitination • positive regulation of proteasomal ubiquitin-dependent protein catabolic process • protein ubiquitination • ubiquitin-dependent protein catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	25820	n/a
Ensembl	ENSG00000166233	n/a
UniProt	Q9Y4X5	n/a
RefSeq (mRNA)	NM_005744	n/a
RefSeq (protein)	NP_005735	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARIH1 yw ARIH1 a elwir hefyd yn Ariadne RBR E3 ubiquitin protein ligase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q24.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARIH1.

• ARI
• HARI
• HHARI
• UBCH7BP

Llyfryddiaeth

• "Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation. ". Cell. 2016. PMID 27565346.
• "Structure of the HHARI catalytic domain shows glimpses of a HECT E3 ligase. ". PLoS One. 2013. PMID 24058416.
• "Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI. ". Nat Commun. 2017. PMID 28790309.
• "Characterisation of the human and mouse orthologues of the Drosophila ariadne gene. ". Cytogenet Cell Genet. 2000. PMID 11124525.
• "Human Homolog of Drosophila Ariadne (HHARI) is a marker of cellular proliferation associated with nuclear bodies.". Exp Cell Res. 2013. PMID 23059369.