ARFGAP1

ARFGAP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3O47, 3DWD
Dynodwyr
Cyfenwau	ARFGAP1, ARF1GAP, HRIHFB2281, ADP ribosylation factor GTPase activating protein 1
Dynodwyr allanol	OMIM: 608377 HomoloGene: 5517 GeneCards: ARFGAP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metal ion binding • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • synapse • Golgi apparatus • cytosol • GO:0097483, GO:0097481 postsynaptic density • Golgi membrane Prosesau biolegol • endoplasmic reticulum to Golgi vesicle-mediated transport • regulation of endocytosis • IRE1-mediated unfolded protein response • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum • protein transport • vesicle-mediated transport • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • regulation of ARF protein signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	55738	n/a
Ensembl	ENSG00000101199	n/a
UniProt	Q8N6T3	n/a
RefSeq (mRNA)	NM_001281482 NM_001281483 NM_001281484 NM_018209 NM_175609	n/a
RefSeq (protein)	NP_001268411 NP_001268412 NP_001268413 NP_060679 NP_783202	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARFGAP1 yw ARFGAP1 a elwir hefyd yn ADP-ribosylation factor GTPase-activating protein 1 ac ADP ribosylation factor GTPase activating protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 20, band 20q13.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARFGAP1.

• ARF1GAP
• HRIHFB2281

Llyfryddiaeth

• "GAP control: regulating the regulators of small GTPases. ". Trends Cell Biol. 2004. PMID 15246431.
• "Expression, purification, and properties of ADP-ribosylation factor (ARF) GTPase activating protein-1. ". Methods Enzymol. 2001. PMID 11210549.
• "ARFGAP1 is dynamically associated with lipid droplets in hepatocytes. ". PLoS One. 2014. PMID 25397679.
• "ArfGAP1 activity and COPI vesicle biogenesis. ". Traffic. 2009. PMID 19055691.
• "Kinetic analysis of Arf GAP1 indicates a regulatory role for coatomer.". J Biol Chem. 2008. PMID 18541532.