APRT

APRT
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1ZN9, 1ORE, 1ZN7, 1ZN8, 4X44, 4X45
Dynodwyr
Cyfenwau	APRT, AMP, APRTD, adenine phosphoribosyltransferase
Dynodwyr allanol	OMIM: 102600 HomoloGene: 413 GeneCards: APRT
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • glycosyltransferase activity • transferase activity • adenine binding • adenine phosphoribosyltransferase activity • AMP binding Cydrannau o'r gell • nucleoplasm • extracellular exosome • extracellular region • cytoplasm • cytosol • secretory granule lumen Prosesau biolegol • grooming behavior • nucleoside metabolic process • purine-containing compound salvage • lactation • purine ribonucleoside salvage • adenine salvage • adenine metabolic process • cellular response to insulin stimulus • AMP salvage • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	353	n/a
Ensembl	ENSG00000198931	n/a
UniProt	P07741	n/a
RefSeq (mRNA)	NM_001030018 NM_000485	n/a
RefSeq (protein)	NP_000476 NP_001025189	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn APRT yw APRT a elwir hefyd yn Adenine phosphoribosyltransferase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 16, band 16q24.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn APRT.

• AMP
• APRTD

Llyfryddiaeth

• "Adenine phosphoribosyltransferase (APRT) deficiency: identification of a novel nonsense mutation. ". BMC Nephrol. 2014. PMID 24986359.
• Adenine Phosphoribosyltransferase Deficiency. 1993. PMID 22934314.
• "A Japanese boy with adenine phosphoribosyltransferase (APRT) deficiency caused by compound heterozygosity including a novel missense mutation in APRT gene. ". Acta Paediatr. 2011. PMID 21635362.
• "The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP. ". Mol Cell Biochem. 2009. PMID 19399589.
• "Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism.". J Biomol Struct Dyn. 2008. PMID 18399692.