AP2B1

AP2B1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1E42, 2G30, 2IV8, 2IV9, 2JKR, 2JKT, 2VGL, 2XA7, 4UQI
Dynodwyr
Cyfenwau	AP2B1, ADTB2, AP105B, AP2-BETA, CLAPB1, adaptor related protein complex 2 beta 1 subunit, adaptor related protein complex 2 subunit beta 1
Dynodwyr allanol	OMIM: 601025 HomoloGene: 68176 GeneCards: AP2B1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • clathrin adaptor activity • GO:0032403 protein-containing complex binding • clathrin binding • signal sequence binding • GO:0001948, GO:0016582 protein binding • cargo receptor activity Cydrannau o'r gell • endocytic vesicle membrane • cytosol • clathrin-coated endocytic vesicle membrane • bilen • clathrin coat • Cellbilen • trans-Golgi network • endolysosome membrane • membrane coat • clathrin-coated pit • clathrin adaptor complex • AP-2 adaptor complex • clathrin-coated endocytic vesicle • postsynapse • glutamatergic synapse Prosesau biolegol • cardiac septum development • endocytosis • ventricular septum development • antigen processing and presentation of exogenous peptide antigen via MHC class II • ephrin receptor signaling pathway • GO:0019049, GO:0030683 mitigation of host defenses by virus • coronary vasculature development • aorta development • heart development • clathrin-dependent endocytosis • clathrin coat assembly • protein transport • intracellular protein transport • vesicle-mediated transport • microtubule-based movement • Wnt signaling pathway, planar cell polarity pathway • membrane organization • neurotransmitter receptor internalization • low-density lipoprotein particle receptor catabolic process • low-density lipoprotein particle clearance • GO:0015915 transport • positive regulation of endocytosis • postsynaptic neurotransmitter receptor internalization • negative regulation of neuron death • positive regulation of protein localization to membrane Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	163	n/a
Ensembl	ENSG00000006125	n/a
UniProt	P63010	n/a
RefSeq (mRNA)	NM_001030006 NM_001282	n/a
RefSeq (protein)	NP_001025177 NP_001273	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn AP2B1 yw AP2B1 a elwir hefyd yn AP-2 complex subunit beta ac Adaptor related protein complex 2 beta 1 subunit (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AP2B1.

• ADTB2
• AP105B
• CLAPB1
• AP2-BETA

Llyfryddiaeth

• "Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. ". Mol Cell Biol. 2006. PMID 16581796.
• "Expression of a novel beta adaptin subunit mRNA splice variant in human testes. ". Asian J Androl. 2005. PMID 15897975.
• "The structure and function of the beta 2-adaptin appendage domain. ". EMBO J. 2000. PMID 10944104.
• "Clathrin adaptors. AP2 controls clathrin polymerization with a membrane-activated switch. ". Science. 2014. PMID 25061211.
• "A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex.". Cell. 2010. PMID 20603002.