AP1B1

AP1B1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4HMY, 4P6Z
Dynodwyr
Cyfenwau	AP1B1, ADTB1, AP105A, BAM22, CLAPB2, adaptor related protein complex 1 beta 1 subunit, adaptor related protein complex 1 subunit beta 1, KIDAR
Dynodwyr allanol	OMIM: 600157 HomoloGene: 21972 GeneCards: AP1B1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transporter activity • GO:0001948, GO:0016582 protein binding • protein kinase binding • clathrin binding Cydrannau o'r gell • trans-Golgi network membrane • bilen • Golgi membrane • lysosomal membrane • clathrin-coated vesicle membrane • membrane coat • cytoplasmic vesicle membrane • GO:0016023 cytoplasmic vesicle • clathrin adaptor complex • Golgi apparatus • cytosol • intracellular membrane-bounded organelle Prosesau biolegol • antigen processing and presentation of exogenous peptide antigen via MHC class II • GO:0019049, GO:0030683 mitigation of host defenses by virus • heart development • determination of left/right symmetry • protein transport • intracellular protein transport • vesicle-mediated transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	162	n/a
Ensembl	ENSG00000100280	n/a
UniProt	Q10567	n/a
RefSeq (mRNA)	NM_145730 NM_001127 NM_001166019	n/a
RefSeq (protein)	NP_001118 NP_001159491 NP_663782 NP_001365491 NP_001365492 NP_001365493 NP_001365494 NP_001365495	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn AP1B1 yw AP1B1 a elwir hefyd yn AP-1 complex subunit beta-1 ac Adaptor related protein complex 1 beta 1 subunit (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q12.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AP1B1.

• ADTB1
• BAM22
• AP105A
• CLAPB2

Llyfryddiaeth

• "Structure of the promoter and genomic organization of the human beta'-adaptin gene (BAM22) from chromosome 22q12. ". Genomics. 1996. PMID 8812422.
• "Basolateral sorting of chloride channel 2 is mediated by interactions between a dileucine motif and the clathrin adaptor AP-1. ". Mol Biol Cell. 2015. PMID 25739457.
• "Basolateral EGF receptor sorting regulated by functionally distinct mechanisms in renal epithelial cells. ". Traffic. 2013. PMID 23205726.
• "Characterization of a new member of the human beta-adaptin gene family from chromosome 22q12, a candidate meningioma gene. ". Hum Mol Genet. 1994. PMID 7987321.
• "ARH cooperates with AP-1B in the exocytosis of LDLR in polarized epithelial cells.". J Cell Biol. 2011. PMID 21444685.