ANP32B

ANP32B
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2ELL, 2RR6
Dynodwyr
Cyfenwau	ANP32B, APRIL, PHAPI2, SSP29, acidic nuclear phosphoprotein 32 family member B
Dynodwyr allanol	HomoloGene: 21286 GeneCards: ANP32B
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0031493 histone binding • GO:0001948, GO:0016582 protein binding • RNA polymerase binding Cydrannau o'r gell • cytoplasm • extracellular exosome • nucleolus • cnewyllyn cell Prosesau biolegol • positive regulation of protein export from nucleus • negative regulation of cell differentiation • inner ear development • nucleosome assembly • roof of mouth development • vasculature development • activation of cysteine-type endopeptidase activity involved in apoptotic process • ventricular system development • GO:0035042 histone exchange Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10541	n/a
Ensembl	ENSG00000136938	n/a
UniProt	Q92688	n/a
RefSeq (mRNA)	NM_006401	n/a
RefSeq (protein)	NP_006392	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ANP32B yw ANP32B a elwir hefyd yn Acidic nuclear phosphoprotein 32 family member B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q22.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ANP32B.

• APRIL
• SSP29
• PHAPI2

Llyfryddiaeth

• "Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) contributes to retinoic acid-induced differentiation of leukemic cells. ". Biochem Biophys Res Commun. 2012. PMID 22705300.
• "Solution structure of histone chaperone ANP32B: interaction with core histones H3-H4 through its acidic concave domain. ". J Mol Biol. 2010. PMID 20538007.
• "Downregulation of ANP32B exerts anti-apoptotic effects in hepatocellular carcinoma. ". PLoS One. 2017. PMID 28486557.
• "Caspase-3-resistant uncleavable form of acidic leucine-rich nuclear phosphoprotein 32B potentiates leukemic cell apoptosis. ". Mol Med Rep. 2015. PMID 25483709.
• "ANP32B is a nuclear target of henipavirus M proteins.". PLoS One. 2014. PMID 24823948.