ANGPT2

ANGPT2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1Z3S, 1Z3U, 2GY7, 4JZC, 4ZFG
Dynodwyr
Cyfenwau	ANGPT2, AGPT2, ANG2, angiopoietin 2, LMPHM10
Dynodwyr allanol	OMIM: 601922 HomoloGene: 22401 GeneCards: ANGPT2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metal ion binding • signaling receptor binding • GO:0001948, GO:0016582 protein binding • receptor tyrosine kinase binding Cydrannau o'r gell • cell projection • cnewyllyn cell • Cellbilen • extracellular region • extracellular space Prosesau biolegol • angiogenesis • response to hypoxia • response to mechanical stimulus • negative regulation of positive chemotaxis • response to radiation • negative regulation of cell-substrate adhesion • GO:0072468 signal transduction • animal organ regeneration • response to activity • Tie signaling pathway • cellular response to growth factor stimulus • multicellular organism development • maternal process involved in female pregnancy • negative regulation of angiogenesis • GO:1904578 response to organic cyclic compound • leukocyte migration • negative regulation of blood vessel endothelial cell migration • blood vessel morphogenesis • germ cell development • positive regulation of angiogenesis • response to glucose • cell differentiation • glomerulus vasculature development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	285	n/a
Ensembl	ENSG00000091879	n/a
UniProt	O15123	n/a
RefSeq (mRNA)	NM_001147 NM_001118887 NM_001118888 NM_001386335 NM_001386336 NM_001386337	n/a
RefSeq (protein)	NP_001112359 NP_001112360 NP_001138	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ANGPT2 yw ANGPT2 a elwir hefyd yn Angiopoietin 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 8, band 8p23.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ANGPT2.

• ANG2
• AGPT2

Llyfryddiaeth

• "The role of serum angiopoietin-2 levels in progression and prognosis of lung cancer: A meta-analysis. ". Medicine (Baltimore). 2017. PMID 28906403.
• "Crosstalk between TEMs and endothelial cells modulates angiogenesis and metastasis via IGF1-IGF1R signalling in epithelial ovarian cancer. ". Br J Cancer. 2017. PMID 28898232.
• "The role of angiopoietin-2 in nucleus pulposus cells during human intervertebral disc degeneration. ". Lab Invest. 2017. PMID 28394321.
• "Angiopoietin-2 Enhances Osteogenic Differentiation of Bone Marrow Stem Cells. ". J Cell Biochem. 2017. PMID 28214341.
• "Identification of ANGPT2 as a New Gene for Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in the Chinese and Japanese Populations.". Invest Ophthalmol Vis Sci. 2017. PMID 28192798.