ALOX5

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ALOX5
3V99 ALOX5.png
Strwythurau
PDBOrthologau:PDBe RCSB
Dynodwyr
CyfenwauALOX5, Alox5, 5-LO, 5-LOX, 5LO, 5LX, AI850497, F730011J02, 5LPG, LOG5, arachidonate 5-lipoxygenase
Dynodwyr allanolMGI: 87999 HomoloGene: 561 GeneCards: ALOX5
Patrwm RNA pattern
PBB GE ALOX5 204445 s at fs.png

PBB GE ALOX5 204446 s at fs.png

PBB GE ALOX5 214366 s at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000698
NM_001256153
NM_001256154
NM_001320861
NM_001320862

NM_009662

RefSeq (protein)

NP_000689
NP_001243082
NP_001243083
NP_001307790
NP_001307791

NP_033792

Lleoliad (UCSC)n/aChr : 116.41 – 116.46 Mb
PubMed search[2][3]
Wicidata
Gweld/Golygu Bod dynolGweld/Golygu Llygoden

Protein sy'n cael ei godio yn y corff dynol gan y genyn ALOX5 yw ALOX5 a elwir hefyd yn Arachidonate 5-lipoxygenase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 10, band 10q11.21.[4]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ALOX5.

  • 5-LO
  • 5LPG
  • LOG5
  • 5-LOX

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Identification and Characterization of a New Protein Isoform of Human 5-Lipoxygenase. ". PLoS One. 2016. PMID 27855198.
  • "5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells. ". BMC Cancer. 2016. PMID 27411387.
  • "Interactions between 5-Lipoxygenase Polymorphisms and Adipose Tissue Contents of Arachidonic and Eicosapentaenoic Acids Do Not Affect Risk of Myocardial Infarction in Middle-Aged Men and Women in a Danish Case-Cohort Study. ". J Nutr. 2017. PMID 28566527.
  • "Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12. ". Biochim Biophys Acta. 2017. PMID 28257804.
  • "Common Polymorphisms in the 5-Lipoxygenase Pathway and Risk of Incident Myocardial Infarction: A Danish Case-Cohort Study.". PLoS One. 2016. PMID 27893808.

Cyfeiriadau[golygu | golygu cod y dudalen]