ALDH1L1

ALDH1L1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2BW0, 2CFI, 2CQ8
Dynodwyr
Cyfenwau	ALDH1L1, 10-FTHFDH, 10-fTHF, FDH, FTHFD, aldehyde dehydrogenase 1 family member L1
Dynodwyr allanol	OMIM: 600249 HomoloGene: 122031 GeneCards: ALDH1L1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • formyltetrahydrofolate dehydrogenase activity • oxidoreductase activity • hydroxymethyl-, formyl- and related transferase activity • catalytic activity • aldehyde dehydrogenase (NAD+) activity • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Cydrannau o'r gell • extracellular exosome • mitocondria • cytoplasm • cytosol Prosesau biolegol • metabolaeth • one-carbon metabolic process • biosynthesis • 10-formyltetrahydrofolate catabolic process • folic acid metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10840	n/a
Ensembl	ENSG00000144908	n/a
UniProt	O75891	n/a
RefSeq (mRNA)	NM_001270364 NM_001270365 NM_012190 NM_144776	n/a
RefSeq (protein)	NP_001257293 NP_001257294 NP_036322	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ALDH1L1 yw ALDH1L1 a elwir hefyd yn Cytosolic 10-formyltetrahydrofolate dehydrogenase ac Aldehyde dehydrogenase 1 family member L1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3q21.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ALDH1L1.

• FDH
• FTHFD
• 10-fTHF
• 10-FTHFDH

Llyfryddiaeth

• "Activation of p21-Dependent G1/G2 Arrest in the Absence of DNA Damage as an Antiapoptotic Response to Metabolic Stress. ". Genes Cancer. 2011. PMID 22593801.
• "Genetic and epigenetic analysis of non-small cell lung cancer with NotI-microarrays. ". Epigenetics. 2012. PMID 22491060.
• "Modeling of interactions between functional domains of ALDH1L1. ". Chem Biol Interact. 2017. PMID 28414156.
• "Association between ALDH1L1 gene polymorphism and neural tube defects in the Chinese Han population. ". Neurol Sci. 2016. PMID 26993122.
• "Division of labour: how does folate metabolism partition between one-carbon metabolism and amino acid oxidation?". Biochem J. 2015. PMID 26567272.